FEAST Study

What is this study about?

The purpose of the FEAST (Focally Electrically-administered Seizure Therapy) research is to find an alternative version of ECT that reduces the negative side effects (mainly memory loss) while still providing patients with relief from depressive symptoms. Previous forms of ECT may use bilateral (electrodes on both sides of the head) or Right Unilateral (electrodes on one side of the head). Our research focuses on adjusting the placement of electrodes on one side of the head in order to better stimulate the Prefrontal Cortex of the brain. 

If you:

• Are between the ages of 22-90 years old

• Have a diagnosis of Major Depressive Disorder (MDD) unresponsive to at least two antidepressants of adequate dose and duration

• Have had a physician state you are a candidate for ECT, you may be interested in this study. 

What will I do if I participate?

The study takes place at St. Louis Park University of Minnesota Physicians Clinic and UMMC North Building on West Bank in Minneapolis. When you participate in this study you will:

• Attend 4 total research visits, 2 of which may be completed virtually Total duration is expected to be up to 8 weeks

• Complete assessments on mood and cognition before and after your treatment

• Undergo pre-ECT medical work up

• Have an interview to review your symptoms

• Receive EEG during procedures

• Have 4 weeks of ECT therapy

Following the ECT therapy, participants will be followed by their clinician and offered appropriate follow up care.