Advancement in Parasitology

Monogenoidea and their environment

Priyanka Tripathi*, Nirupama Agrawal

Abstract

Studies on some monogenoideans were carried out in laboratory, maintaining some fresh-water fishes

in laboratory.

Antileishmanial and Insecticidal activities of some Medicinal plants of Pakistan

Yusra Ali*, Baqir Shyum Naqvi, Ghazala H. Rizwani, Bushra Hina, Aamir Shadmani

Abstract

World Health Organization has identified leishmaniasis as a major public health problem. Due to expensive treatment and absence of vaccine resistance has been developed against leishmania parasite. The aim of this research is to search new antileishmanial drug (plant kingdom). Herbal medicines showing more momentum regarding the cure of various infectious diseases such as (leishmaniasis, eczema and other bacterial and fungal infections).Therefore in present study we selected methanolic extracts of some medicinal plants (I-V) (Casuarina equisetifolia L. (I), Mirabilis jalapa L. (II), Calotropis procera (Ait) (III), Nerium oleander L. (IV) and Thespesia populnea L. (V)) for antileishmanial activity against (L. Major) in 96 well micro titer plate bioassay. I and II showed good leishmanicidal activities with IC50 values of 39.95μg/ml and 38.4μg/ml respectively. We also performed insecticidal activity of these plant extracts by direct contact method. Insecticidal activity of methanolic extracts of (I, II, III, IV and V) drugs, II and V showed 20% mortality against Rhyzopertha dominica, while I, III and IV found to be safe. methanolic bark extract of Casuarina equisetifolia L. (I) is subjected to heavy metal detection through atomic absorption spectroscopic technique. The outcomes of this research indicate valuable and safe antileishmanial agent.