3D UMAP Classification of UniRef 100 of "Cytochrome P450"
3D UMAP Classification of UniRef 100 of "Cytochrome P450"
Embedded Files
3D_CLASS 0 P450 (RXC Rich)
2D_Class03D_CLASS 0 P450 (RXC Rich)
3D_Class0
3D_Class0
Compornents of 2D_Class
Compornents of 2D_Class
CLASS 1 P450 (HXC)
2D_Class2 (HXC)CLASS 1 P450 (HXC)
3D_Class Name
3D_Class Name
Compornents of 2D_Class
Compornents of 2D_Class
CLASS 2 P450 (Partial Protein and CYP152s)
2D_Class0CLASS 2 P450 (Partial Protein and CYP152s)
3D_Class Name
3D_Class Name
Compornents of 2D_Class
Compornents of 2D_Class
CLASS 3 P450 (RXC)
2D_Class1 (RXC)CLASS 3 P450 (RXC)
2D_Class Name
2D_Class Name
Compornents of 2D_Class
Compornents of 2D_Class
CLASS 4 DBSCAN_Out Group
CLASS 4 DBSCAN_Out Group
CLASS 6_P450 and Other Proteins (Two Group)
2D_Class4 Partial protein (<350aa)2D_Class7 Partial protein (<350aa)2D_Class1 (RXC)CLASS 6_P450 and Other Proteins (Two Group)
CLASS 6_Fungal P450
2D_Class5 Fungal P450CLASS 6_Fungal P450
CLASS 7_Cytochrome P450 Reductase (CPR)
2D_Class8 CPR2D_Class11 CPRCLASS 7_Cytochrome P450 Reductase (CPR)
CLASS 8_Plant P450
2D_Class1 (RXC)CLASS 8_Plant P450
CLASS 9_Arthropod P450
2D_Class1 (RXC)CLASS 9_Arthropod P450
CLASS 10_Fungal P450-CPR Fusion
2D_Class12 (RXC)2D_Class14 (RXC)CLASS 10_Fungal P450-CPR Fusion
CLASS 11_Bacterial P450
2D_Class10 StreptomycesCLASS 11_Bacterial P450
CLASS 12_Fish P450
2D_Class1 (RXC)CLASS 12_Fish P450
CLASS 13_CPR-Fusion P450 (Bacterial)
2D_Class15 (RXC)2D_Class14 (RXC)CLASS 13_CPR-Fusion P450 (Bacterial)
CLASS 14_Fish P450
2D_Class1 (RXC)CLASS 14_Fish P450
CLASS 15_Plant P450
2D_Class1 (RXC)CLASS 15_Plant P450
CLASS 16_CPR-Fusion P450 (Fungal)
2D_Class9 (RXC)CLASS 16_CPR-Fusion P450 (Fungal)
CLASS 17_Fish P450
2D_Class1 (RXC)CLASS 17_Fish P450
CLASS 18_Plant P450
2D_Class1 (RXC)CLASS 18_Plant P450
CLASS 19_Fungal P450
2D_Class1 (RXC)CLASS 19_Fungal P450
CLASS 20_Archaea P450
2D_Class0 (RXC)CLASS 20_Archaea P450
Reference
Cytochrome P450 HomepageNelson, DR (2009) The Cytochrome P450 Homepage. Human Genomics 4, 59-65.Comprehensive Bacterial P450shttps://drnelson.uthsc.edu/comprehensive-bacterial-p450s/Reference
UniRepUnified rational protein engineering with sequence-based deep representation learningEthan C. Alley et al, (2019) Nat Methods 16, 1315–1322
https://doi.org/10.1038/s41592-019-0598-1
UMAP
https://github.com/lmcinnes/umap
DBSCAN
https://github.com/mhahsler/dbscan
D. R. Nelson's Data Base
D. R. Nelson's Data Base
https://twitter.com/P450nelson/status/1501396401317883904
2D UMAP Classification of UniRef 100 of "Cytochrome P450"
2D UMAP Classification of UniRef 100 of "Cytochrome P450"
2D_Class0 P450 (R/H) 2D_Class10 P450 (H)
2D_Class0 P450 (R/H) 2D_Class10 P450 (H)
2D_Class1 P450 (R) 2D_Class11 P450-CPR Fusion
2D_Class1 P450 (R) 2D_Class11 P450-CPR Fusion
2D_Class2 P450 (H) 2D_Class12 Fungal P450-CPR Fusion (R)
2D_Class2 P450 (H) 2D_Class12 Fungal P450-CPR Fusion (R)
2D_Class3 DBSCAN Out Group 2D_Class13 P450 (R)
2D_Class3 DBSCAN Out Group 2D_Class13 P450 (R)
2D_Class4 Partial 2D_Class14 Fungal P450-CPR Fusion (R)
2D_Class4 Partial 2D_Class14 Fungal P450-CPR Fusion (R)
2D_Class5 P450 (R) Fungal 2D_Class15 Fungal P450-CPR Fusion (R)
2D_Class5 P450 (R) Fungal 2D_Class15 Fungal P450-CPR Fusion (R)
2D_Class6 Partial 2D_Class16 P450 (R)
2D_Class6 Partial 2D_Class16 P450 (R)
2D_Class7 Partial 2D_Class17
2D_Class7 Partial 2D_Class17
2D_Class8 CPR 2D_Class18
2D_Class8 CPR 2D_Class18
2D_Class9 P450 (R) 2D_Class19 P450 (H)
2D_Class9 P450 (R) 2D_Class19 P450 (H)
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