Frontier Central High School, Hamburg, NY
Frontier Central High School, Hamburg, NY
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The Western New York Genetics in Research and Health Care Partnership Virtual Capstone
Elizabeth Brombos is a junior at Frontier High School. She dreams of being an anesthesiologist in the future, but her short-term goal is to spend the summer tanning on the beach.
Jaclyn Conley is a sophomore at Frontier High School. Due to the COVID pandemic, her primary goal is to have a happy and healthy next two years of high school. She also plans to take quite a few science classes in the future and rev up her school’s newspaper.
Annotation of Locus Tags PA0021 from Pseudomonas aeruginosa Genome and BH_RS00190 from Bartonella henselae Genome
Advisor: Vanessa Rich
Student Researchers: Elizabeth Brombos and Jaclyn Conley
Abstract: A gene sequence from Bartonella Henselae str. Houston-1 (BH_RS00190) and Pseudomonas aeruginosa (PA0021) were annotated using the collaborative genome annotation website GENI-ACT. The Genbank proposed gene product name for each gene was assessed in terms of the general genomic information, amino acid sequence-based similarity data, structure-based evidence from the amino acid sequence, cellular localization data, potential alternative open reading frames, and enzymatic function. The Genbank proposed gene product name did not differ significantly from the proposed gene annotation for BH_RS00190 and as such, the gene appears to be correctly annotated by the nr database. However, there is a change in annotation for PA0021 from a hypothetical protein to a DNA protecting-binding protein, DprA.
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