Tomohiro Furuki, Azusa Togo, Hatsuho Usuda, Tomohiro Nobeyama, Atsushi Hirano, Kentaro Shiraki. Monovalent Ion Effect on Liquid–Liquid Phase Separation of Aqueous Polyphosphate–Salt Mixtures. The Journal of Physical Chemistry B 128 (46), 11435-11440 (2024)

Tsutomu Arakawa, Yui Tomioka, Teruo Akuta, Kentaro Shiraki. The contrasting roles of co-solvents in protein formulations and food products. Biophysical Chemistry, 107282 (2024)

Tomohiro Furuki, Tomohiro Nobeyama, Shunji Suetaka, Ryokei Matsui, Tatsuhiko Fukuoka, Munehito Arai, Kentaro Shiraki. Reentrant condensation of a multicomponent cola/milk system induced by polyphosphate. Food Chemistry: X 21, 101165 (2024)

Toya Yoshida, Nanako Sakakibara, Tomoto Ura, Tsukuru Minamiki, Kentaro Shiraki. Cationic polyelectrolytes prevent the aggregation of l-lactate dehydrogenase under unstable conditions. International Journal of Biological Macromolecules 257, 128549 (2024)

Tomohiro Nobeyama, Toya Yoshida, Kentaro Shiraki. Interfacial and intrinsic molecular effects on the phase separation/transition of heteroprotein condensates. International Journal of Biological Macromolecules 254, 128095 (2024)

Tomohiro Nobeyama, Koji Tataka, Megumi Mori, Tatsuya Murakami, Yoichi Yamada, Kentaro Shiraki. Synthesis of Butterfly‐Like Shaped Gold Nanomaterial: For the Regulation of Liquid–Liquid Phase‐Separated Biomacromolecule Droplets. Small 19 (49), 2300362 (2023)

Tomohiro Nobeyama, Tomohiro Furuki, Kentaro Shiraki. Phase-Diagram Observation of Liquid–Liquid Phase Separation in the Poly(l-lysine)/ATP System and a Proposal for Diagram-Based Application Strategy. Langmuir 39 (48), 17043-17049 (2023)

Atsushi Hirano, Shogo Kanoh, Kentaro Shiraki, Momoyo Wada, Masahiro Kitamura, Katsuya Kato. Selective and high-capacity binding of immunoglobulin G to zirconia nanoparticles modified with phosphate groups. Colloids and Surfaces B: Biointerfaces 226, 113291 (2023)

Hayato Nagano, Teruhisa Mannen, Yoshimi Kikuchi, Kentaro Shiraki. The pH-responsive precipitation–redissolution of the CspB fusion protein, CspB50TEV-Teriparatide, triggered by changes in secondary structure. Biochemistry and Biophysics Reports 33, 101435 (2023)

Tomoto Ura, Ako Kagawa, Nanako Sakakibara, Hiromasa Yagi, Naoya Tochio, Takanori Kigawa, Kentaro Shiraki, Tsutomu Mikawa. Activation of L-lactate oxidase by the formation of enzyme assemblies through liquid–liquid phase separation. Scientific Reports 13 (1), 1435 (2023)

Yuto Akahoshi, Hiroka Sugai, Masahiro Mimura, Yoichi Shinkai, Ryoji Kurita, Kentaro Shiraki, Shunsuke Tomita. Phase-separation propensity of non-ionic amino acids in peptide-based complex coacervation systems. Biomacromolecules 24 (2), 704-713 (2023)

Hiroshi Kano, Kentaro Shiraki. Heat treatment in the presence of arginine increases the emulsifying properties of soy proteins. Food Chemistry: X, 100567 (2023)

Tomoto Ura, Tomoshi Kameda, Fina A Laksmi, Matsujiro Ishibashi, Tsutomu Arakawa, Kentaro Shiraki, Atsushi Hirano. Affinity of phenolic compounds for transition metal ions immobilized on cation-exchange columns. Journal of Chromatography A 1676, 463277 (2022)

Keijiro Ohshima, Tomoko Ohshima, Karen Meyer, Eisuke Takai, Shunsuke Yoshizawa, Kentaro Shiraki, Nobuko Maeda. Proteome analysis of high affinity mouse saliva proteins to hydroxyapatite. Heliyon 8 (8), e10077 (2022)

Akira Nomoto, Suguru Nishinami, Kentaro Shiraki. Affinity of aromatic amino acid side chains in amino acid solvents. Biophysical Chemistry 287, 106831 (2022)

Hayato Nagano, Teruhisa Mannen, Yoshimi Kikuchi, Kentaro Shiraki. Solution design to extend the pH range of the pH-responsive precipitation of a CspB fusion protein. Protein Expression and Purification 195, 106091 (2022)

Hiroka Sugai, Shunsuke Tomita, Sayaka Ishihara, Kentaro Shiraki, Ryoji Kurita. Damage-free evaluation of cultured cells based on multivariate analysis with a single-polymer probe. Chemical Communications 58 (79), 11083-11086 (2022)

Wakako Mori, Ryosuke Kawakami, Yosuke Niko, Tomohiro Haruta, Takeshi Imamura, Kentaro Shiraki, Tamotsu Zako. Differences in interaction lead to the formation of different types of insulin amyloid. Scientific Reports 12 (1), 1-15 (2022)

Keisuke Tsumura, WeiLin Hsu, Masahiro Mimura, Aiko Horiuchi, Kentaro Shiraki. Lowering the viscosity of a high-concentration antibody solution by protein–polyelectrolyte complex. Journal of bioscience and bioengineering, 133, 17-24 (2022)

Shogo Oki, Suguru Nishinami, Yoshitaka Nakauchi, Toshihiko Ogura, Kentaro Shiraki. Arginine and its Derivatives Suppress the Opalescence of an Antibody Solution. Journal of Pharmaceutical Sciences, 111, 1126-1132 (2022)

Suguru Nishinami, Tsutomu Arakawa, Kentaro Shiraki. Classification of protein solubilizing additives by fluorescence assay. International Journal of Biological Macromolecules 203, 695-702 (2022)

Yoshitaka Nakauchi, Suguru Nishinami, Yusuke Murakami, Toshihiko Ogura, Hideaki Kano, Kentaro Shiraki. Opalescence Arising from Network Assembly in Antibody Solution. Molecular Pharmaceutics, (2022)

Yoshitaka Nakauchi, Suguru Nishinami, Yusuke Murakami, Toshihiko Ogura, Hideaki Kano, Kentaro Shiraki. Opalescence Arising from Network Assembly in Antibody Solution. Molecular Pharmaceutics, (2022)

Shogo Oki, Suguru Nishinami, Yoshitaka Nakauchi, Toshihiko Ogura, Kentaro Shiraki. Arginine and its Derivatives Suppress the Opalescence of an Antibody Solution. Journal of Pharmaceutical Sciences, 111, 1126-1132 (2022)

Suguru Nishinami, Tsutomu Arakawa, Kentaro Shiraki. Classification of protein solubilizing additives by fluorescence assay. International Journal of Biological Macromolecules 203, 695-702 (2022)

Yoshitaka Nakauchi, Suguru Nishinami, Yusuke Murakami, Toshihiko Ogura, Hideaki Kano, Kentaro Shiraki. Opalescence Arising from Network Assembly in Antibody Solution. Molecular Pharmaceutics, (2022)

Yoshitaka Nakauchi, Suguru Nishinami, Yusuke Murakami, Toshihiko Ogura, Hideaki Kano, Kentaro Shiraki. Opalescence Arising from Network Assembly in Antibody Solution. Molecular Pharmaceutics, (2022)

Akira Nomoto, Suguru Nishinami, Kentaro Shiraki. Solubility Parameters of Amino Acids on Liquid–Liquid Phase Separation and Aggregation of Proteins. Frontiers in cell and developmental biology 9, 691052 (2021)

Suguru Nishinami, Keiko Ikeda, Tamiko Nagao, A Hajime Koyama, Tsutomu Arakawa, Kentaro Shiraki. Aromatic interaction of hydantoin compounds leads to virucidal activities. Biophysical Chemistry, 106621(2021)

Yoshitaka Nakauchi, Suguru Nishinami, KentaroShiraki. Glass-like protein condensate for the long-term storage of proteins. International Journal of Biological Macromolecules. (2021)

Taehun Hong, Kazuki Iwashita, Jeungmin Han, Suguru Nishinami, Akihiro Handa, Kentaro Shiraki. Aggregation of Hen Egg White Proteins with Additives During Agitation. LWT, 111378 (2021)

Yuji Itoh, Shiori Iida, Sachiko Tamura, Ryosuke Nagashima, Kentaro Shiraki, Tatsuhiko Goto, Kayo Hibino, Satoru Ide, Kazuhiro Maeshima. 1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells. Life Sci Alliance. 4(4):e202001005 (2021)

Tatsuya Mori, Yue Jiang, Yasuhiro Fujii, Suguru Kitani, Hideyuki Mizuno, Akitoshi Koreeda, Leona Motoji, Hiroko Tokoro, Kentaro Shiraki, Yohei Yamamoto, Seiji Kojima. Detection of boson peak and fractal dynamics of disordered systems using terahertz spectroscopy. Physical Review E, 102, 022502 (2020)

Eiko N Minakawa, Helena Akiko Popiel, Masayoshi Tada, Toshiaki Takahashi, Hiroshi Yamane, Yuji Saitoh, Yasuo Takahashi, Daisaku Ozawa, Akiko Takeda, Toshihide Takeuchi, Yuma Okamoto, Kazuhiro Yamamoto, Mari Suzuki, Hiromi Fujita, Chiyomi Ito, Hiroko Yagihara, Yuko Saito, Kei Watase, Hiroaki Adachi, Masahisa Katsuno, Hideki Mochizuki, Kentaro Shiraki, Gen Sobue, Tatsushi Toda, Keiji Wada, Osamu Onodera, Yoshitaka Nagai. Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation. Brain 143, 1811-1825 (2020)

Kentaro Shiraki, Masahiro Mimura, Suguru Nishinami, Tomoto Ura. Effect of additives on liquid droplets and aggregates of proteins. Biophysical Review 12, 587-592 (2020)

Suguru Nishinami, Tomoshi Kameda, Tsutomu Arakawa, and Kentaro Shiraki. Hydantoin and Its Derivatives Reduce the Viscosity of Concentrated Antibody Formulations by Inhibiting Associations via Hydrophobic Amino Acid Residues. Ind. Eng. Chem. Res, 58, 36, 16296-16306 (2019)

Shunsuke Tomita, Hiroka Sugai, Masahiro Mimura, Sayaka Ishihara, Kentaro Shiraki, Ryoji Kurita. Optical Fingerprints of Proteases and Their Inhibited Complexes Provided by Differential Cross-Reactivity of Fluorophore-Labeled Single-Stranded DNA. ACS Appl Mater Interfaces, 11(50):47428–47436 (2019)

Chika Shibata, Kazuki Iwashita, Kentaro Shiraki. Salt-containing aqueous two-phase system shows predictable partition of proteins with surface amino acids residues. Int. J. Biol. Macromol., 133, 1182-1186 (2019)

Chika Shibata, Kazuki Iwashita, Kentaro Shiraki. Selective separation method of aggregates from IgG solution by aqueous two-phase system. Protein Expr Purif. 161, 57-62 (2019)

Atsushi Hirano, Kazuki Iwashita, Tomoto Ura, Shun Sakuraba, Kentaro Shiraki, Tsutomu Arakawa, Tomoshi Kameda. Binding affinity of uncharged aromatic solutes for negatively charged resins is enhanced by cations through cation–pai interaction: the case of sodium ion and arginine. J. Chromato. A, 1595 97–107 (2019)

Masahiro Mimura, Keisuke Tsumura, Ayumi Matsuda, Naoki Akatsuka, and Kentaro Shiraki. Effect of additives on liquid droplet of protein–polyelectrolyte complex for high-concentration formulations. J Chem Phys. 150, 064903 (2019)

Kazuki Iwashita, Akihiro Handa, Kentaro Shiraki. Co-aggregation of ovotransferrin and lysozyme. Food Hydrocolloids, 89, 416-424 (2019)

Miki Nemoto, Kazunori Sugihara, Tsubasa Adachi, Kazuki Murata, Kentaro Shiraki, and Seiya Tsujimura. Effect of electrolyte ions on stability of flavin adenine dinucleotide-dependent glucose dehydrogenase, ChemElectroChem, 6, 1028-1031(2019)

Masahiro Mimura, Shunsuke Tomita, Ryoji Kurita, and Kentaro Shiraki. Array-based generation of response fingerprints with common fluorescent dyes for identification of proteins and cells. Anal Sci. 35, 99-102 (2019)

Takahiro Nonaka, Noriko Tsurui, Teruhisa Mannem, Yoshimi Kikuchi, Kentaro Shiraki. Non-chromatographic purification of teriparatide with a pH-responsive CspB tag. Protein Expr. Purif. 155, 66-71 (2019)

Tsutomu Arakawa, Masao Tokunaga, Takuya Maruyama, Kentaro Shiraki. Two Elution Mechanisms of MEP Chromatography. Curr Protein Pept Sci. 20, 28-33 (2019)

Atsushi Hirano, Kentaro Shiraki, and Tomoshi Kameda. Effects of Arginine on Multimodal Chromatography: Experiments and Simulations, Curr Protein Pept Sci. 20, 40-48 (2019)

Kazuki Iwashita, Masahiro Mimura, Kentaro Shiraki. Control of aggregation, co-aggregation, and liquid droplet of proteins by small additives. Curr Pharm Biotechnol. 19, 946-955 (2018), review

Shogo Oki, Suguru Nishinami, Kentaro Shiraki. Arginine suppresses opalescence and liquid–liquid phase separation in IgG solutions. Int. J. Biol. Macromol. 118, 1708-1712 (2018)

Ayumi Matsuda, Masahiro Mimura, Takuya Maruyama, Takaaki Kurinomaru, Shiuhei Mieda, and Kentaro Shiraki. Liquid Droplet of Protein–Polyelectrolyte Complex for High-Concentration Formulations. Journal of Pharmaceutical Sciences, 107, 2713-2719 (2018)

Tomohito Nakayama, Takeshi Tanaka, Kentaro Shiraki, Muneaki Hase, and Atsushi Hirano. Suppression of single-wall carbon nanotube redox reaction caused by protein adsorption. Applied Physics Express 11, 075101 (2018)

Akihiro Endo, Takaaki Kurinomaru, and Kentaro Shiraki. Hyperactivation of serine protease by the Hofmeister effect. Molecular Catalysis, 455, 32-37 (2018)

Kazuki Iwashita, Akihiro Handa, Kentaro Shiraki. Coacervates and coaggregates: Liquid-liquid and liquid-solid phase transitions by native and unfolded protein complexes. Int. J. Biol. Macromol. 120, 10-18 (2018)

Suguru Nishinami, Atsushi Hirano, Tsutomu Arakawa, and Kentaro Shiraki. Effects of allantoin and dimethyl sulfoxide on the thermal aggregation of lysozyme. Int. J. Biol. Macromol., 119, 180-185 (2018)

Suguru Nishinami, Shunsuke Yoshizawa, Tsutomu Arakawa and Kentaro Shiraki. Allantoin and hydantoin as new protein aggregation suppressors. Int. J. Biol. Macromol., 114, 497-503 (2018)

Taehun Hong, Kazuki Iwashita, Kentaro Shiraki. Viscosity Control of Protein Solution by Small Solutes: A Review. Current Protein and Peptide Science, 19, 746-758 (2018)

Atsushi Hirano, Kazuki Iwashita, Shun Sakuraba, Kentaro Shiraki, Tsutomu Arakawa, Tomoshi Kameda. Salt-dependent Elution of Uncharged Aromatic Solutes in Ion-exchange Chromatography. Journal of Chromatography A, 1546, 46-55 (2018)

Shogo Oki, Takahiro Nonaka, Kentaro Shiraki. Specific solubilization of aromatic impurities in culture media: Arg solution improves purification of pH-responsive tag CspB50 with Teriparatide. Protein Expression and Purification 146, 85-90 (2018)

Takahiro Nonaka, Noriko Tsurui, Teruhisa Mannem, Yoshimi Kikuchi, Kentaro Shiraki. A new pH-responsive peptide tag for protein purification. Protein Expression and Purification 146, 91-96 (2018)

Shunsuke Yoshizawa, Shogo Oki, Tsutomu, Arakawa, and Kentaro Shiraki. Trimethylamine N-oxide (TMAO) is a counteracting solute of benzyl alcohol for multi-dose formulation of immunoglobulin. Int. J. Biol. Macromol., 107, 984-989 (2018)

Shogo Oki, Kazuki Iwashita, Masahiro Kimura, Hideaki Kano, Kentaro Shiraki. Mechanism of co-aggregation in a protein mixture with small additives. Int. J. Biol. Macromol., 107, 1428-1437 (2018)

Shunsuke Tomita, Ayumi Matsuda, Suguru Nishinami, Ryoji Kurita, Kentaro Shiraki. One-step identification of antibody degradation pathways using fluo-rescence signatures generated by cross-reactive DNA-based arrays. Anal. Chem. 89, 7818-7822 (2017)

Tomohito Nakayama, Shunsuke Yoshizawa, Atsushi Hirano, Takeshi Tanaka, Kentaro Shiraki, Muneaki Hase. Vibrational Energy Transfer from Photo-Excited Carbon Nanotubes to Proteins Observed by Coherent Phonon Spectroscopy. Applied Physics Express, 10 (12), 125101 (2017)

Shunsuke Yoshizawa, Tsutomu Arakawa, and Kentaro Shiraki. Thermal Aggregation of Human Immunoglobulin G in Arginine Solutions: Contrasting Effects of Stabilizers and Destabilizers, Int. J. Biol. Macromol., 104, 650–655 (2017)

Takaaki Kurinomaru, Kengo Kuwada, Shunsuke Tomita, Tomoshi Kameda and Kentaro Shiraki. Noncovalent PEGylation through Protein-Polyelectrolyte Interaction: Kinetic Experiment and Molecular Dynamics Simulation, J. Phys. Chem. B. 121, 6785-6791 (2017)

Kazuki Iwashita, Akihiro Handa, Kentaro Shiraki. Co-aggregation of ovalbumin and lysozyme. Food Hydrocolloids, 67 206-215 (2017)

Atsushi Hirano, Takuya Maruyama, Kentaro Shiraki, Tsutomu Arakawa, and Tomoshi Kameda. A Study of the Small-Molecule System Used to Investigate the Effect of Arginine on Antibody Elution in Hydrophobic Charge-Induction Chromatography. Protein Expr Purif, 129, 44-52 (2017)

Taehun Hong, Kazuki Iwashita, Akihiro Handa, Kentaro Shiraki. Arginine prevents thermal aggregation of hen egg white proteins. Food Research International, 97, 272-279 (2017)

Takaaki Kurinomaru and Kentaro Shiraki. Aggregative protein-polyelectrolyte complex for high-concentration formulation of protein drug. Int. J. Biol. Macromol.,100 (2017) 11–17

Akihiro Endo, Takaaki Kurinomaru, and Kentaro Shiraki. Hyperactivation of α-chymotrypsin by the Hofmeister effect. J. Mol. Catal. B: Enzymatic, 133, 432-438 (2016)

Kazuki Iwashita, Motoki Sumida, Kazuya Shirota, and Kentaro Shiraki. A recovery method of surimi wash-water protein by pH shift and heat treatment. Food Science and Technology Research, 22 (6), 743-749 (2016)

Shogo Oki, Tsutomu Arakawa, Kentaro Shiraki. The effects of n-acetyltryptophan and caprylic acid on protein aggregation. J. Biol. Macromol. 16, 3-7 (2016)

Kengo Kuwada, Takaaki Kurinomaru, Shunsuke Tomita, and Kentaro Shiraki. Noncovalent PEGylation-based enzyme switch in physiological saline conditions using quaternized polyamines. Colloid and Polymer Science, 296, 1551-1556 (2016)

Shunsuke Yoshizawa, Tsutomu Arakawa, and Kentaro Shiraki. Effect of counter ions of arginine as an additive for the solubilization of protein and aromatic compounds. Int. J. Biol. Macromol. 91, 471-476 (2016)

Katsuyoshi Aoki, Kentaro Shiraki, and Toshiaki Hattori. Salt effects on the picosecond dynamics of lysozyme hydration water investigated by terahertz time-domain spectroscopy and an insight into Hofmeister series for protein stability and solubility. Physical Chemistry Chemical Physics, 18, 15060-15069 (2016)

Kazuki Iwashita, Kentaro Shiraki, Rieko Ishii, Takeshi Tanaka, Atsushi Hirano. Arginine Suppresses the Adsorption of Lysozyme on Single-Wall Carbon Nanotube. Chem. Lett. 45, 952-954 (2016)

Takumi Miyatake, Shunsuke Yoshizawa, Tsutomu Arakawa, Kentaro Shiraki. Charge state of arginine as an additive on heat-induced protein aggregation. Int. J. Biol. Macromol. 87, 563-569 (2016)

Kentaro Shiraki, Takaaki Kurinomaru, and Shunsuke Tomita. Wrap-and-Strip Technology of Protein-Polyelectrolyte Complex for Biomedical Application. Curr. Med. Chem., 23, 276-289 (2016), review

Kentaro Shiraki, Shunsuke Tomita, and Naoto Inoue. Small Amine Molecules: Solvent Design Toward Facile Improvement of Protein Stability Against Aggregation and Inactivation. Curr. Pharm. Biotechnol. 17, 116-125 (2016), review

Kazuki Iwashita, Kentaro Shiraki, Rieko Ishii, Takeshi Tanaka, Atsushi Hirano. Liquid chromatographic analysis of the interaction between amino acids and aromatic surfaces using single-wall carbon nanotubes. Langmuir. 31, 8923-8929 (2015)

Shunsuke Izaki, Takaaki Kurinomaru, Kenji Handa, Tomoaki Kimoto, and Kentaro Shiraki. Stress Tolerance of Antibody-Poly(amino acid) Complexes for Improving the Stability of High Concentration Antibody Formulations. J. Pharm. Sci. 104, 2457-2463 (2015)

Kazuki Iwashita, Naoto Inoue, Akihiro Handa, and Kentaro Shiraki. Thermal aggregation of hen egg white proteins in the presence of salts. Protein J. 34, 212-219 (2015)

Takuya Maruyama, Shunsuke Izaki, Takaaki Kurinomarua, Kenji Handa, Tomoaki Kimoto, and Kentaro Shiraki. Protein-poly(amino acid) precipitation stabilizes a therapeutic protein of L-asparaginase against physicochemical stress. J. Biosci. Bioeng. 120, 720-723 (2015)

Takaaki Kurinomaru, Tomoshi Kameda, and Kentaro Shiraki. Effects of Hydrophobicity and Multivalency of Polyamines on Enzyme Hyperactivation of alpha-Chymotrypsin. J. Mol. Catal. B: Enzymatic. 115, 135-139 (2015)

Shunsuke Izaki, Takaaki Kurinomaru, Takuya Maruyama, Kenji Handa, Tomoaki Kimoto and Kentaro Shiraki. Feasibility of Antibody-Poly(amino acid) Complexes: Preparation of High-concentration Antibody Formulations and their Pharmaceutical Properties. J. Pharm. Sci. 104, 1929-37 (2015)

Masato Shimada, Eisuke Takai, Daisuke Ejima, Tsutomu Arakawa and Kentaro Shiraki. Heat-induced formation of myosin oligomer-soluble filament complex in high salt solution. Int. J. Biol. Macromol. 73, 17-22 (2015)

Takaaki Kurinomaru and Kentaro Shiraki. Non-covalent PEGylation of L-Asparaginase Using PEGylated Polyelectrolyte. J. Pharm. Sci. 104, 587-592 (2015)

Atsushi Hirano, Takuya Maruyama, Kentaro Shiraki, Tsutomu Arakawa, and Tomoshi Kameda. Mechanism of Protein Desorption from 4-Mercaptoethylpyridine Resins by Arginine Solutions. J. Chromato. A, 1373, 141-148 (2014)

Toru Nakayama, Taro Sakuraba, Shunsuke Tomita, Akira Kaneko, Eisuke Takai, Kentaro Shiraki, Kentaro Tashiro, Noriyuki Ishii, Yuri Hasegawa, Yoichi Yamada, Reiji Kumai, and Yohei Yamamoto. Charge-Separated Fmoc-Peptide beta-Sheets: Sequence-Secondary Structure Relationship for Arranging Charged Side Chains on Both Sides .Asian J. Org. Chem., 3, 1182-1188 (2014)

Eisuke Takai, Tsuyoshi Kitamura, Junpei Kuwabara, Satoshi Ikawa, Shunsuke Yoshizawa, Kentaro Shiraki, Hideya Kawasaki, Ryuichi Arakawa, and Katsuhisa Kitano. Chemical Modification of Amino Acids by Atmospheric-Pressure Cold Plasma in Aqueous Solution. J. Phys. D: Appl. Phys. 47, 285403 (2014)

Shunsuke Tomita, Tomohiro Soejima, Kentaro Shiraki and Keitaro Yoshimoto. Enzymatic fingerprinting of structurally similar homologous proteins using polyion complex library constructed by tuning PEGylated polyamine functionalities. Analyst. 139, 6100-6103 (2014)

Naoto Inoue, Eisuke Takai, Tsutomu Arakawa, and Kentaro Shiraki. Specific decrease in solution viscosity of antibodies by arginine for therapeutic formulations. Molecular Pharmaceutics 11, 1889-1896 (2014)

Katsuhisa Murakami, Tianchen Dong, Yuya Kajiwara, Takaki Hiyama, Teppei Takahashi, Eisuke Takai, Gai Ohashi, Kentaro Shiraki, and Jun-ichi Fujita. Synthesis of graphene nanoribbons from amyloid templates by gallium vapor-assisted solid-phase graphitization. Appl. Phys. Lett. 104, 243101 (2014)

Takaaki Kurinomaru, Takuya Maruyama, Shunsuke Izaki, Kenji Handa, Tomoaki Kimoto, and Kentaro Shiraki. Protein-Poly(amino acid) Complex Precipitation for High-concentration Protein Formulation. J. Pharm. Sci. 103, 2248-2254 (2014)

Shunsuke Yoshizawa, Tsutomu Arakawa, and Kentaro Shiraki. Dependence of ethanol effects on protein charges. Int. J. Biological Macromolecules. 68, 169-172 (2014)

Takaaki Kurinomaru, Shunsuke Tomita, Yoshihisa Hagihara, and Kentaro Shiraki. Enzyme Hyperactivation System Based on Generated Reaction Field by Polyelectrolyte. Langmuir 30, 3826-3831 (2014)

Eisuke Takai, Gai Ohashi, Ryuichi Ueki, Yoichi Yamada, Jun-ichi Fujita, Kentaro Shiraki. Scanning Electron Microscope Imaging of Amyloid Fibrils. Am. J. Biochem. Biotechnol. 10, 31-39, (2014)

Eisuke Takai, Ken Uda, Shuhei Matsushita, Yui Shikiya, Yoichi Yamada, Tamotsu Zako, Mizuo Maeda, Kentaro Shiraki, Cysteine Inhibits Amyloid Fibrillation of the Lysozyme and Directs the Formation of Small Worm-like Aggregates through Non-Covalent Interactions. Biotechnol. Prog. 30, 470-478 (2014)

Eisuke Takai, Ken Uda, Tomonori Yoshida, Tamotsu Zako, Mizuo Maeda, Kentaro Shiraki, Cysteine Inhibits the Fibrillisation and Cytotoxicity of Amyloid-beta 40 and 42: Implications for the Contribution of the Thiophilic Interaction. Physical Chemistry Chemical Physics 16, 3566 - 3572 (2014)

Eisuke Takai, Gai Ohashi, Tomonori Yoshida, Karin Margareta Sorgjerd, Tamotsu Zako, Mizuo Maeda, Katsuhisa Kitano, Kentaro Shiraki, Degeneration of Amyloid-beta Fibrils Caused by Exposure to Low-Temperature Atmospheric-Pressure Plasma in Aqueous Solution. Applied Physics Letters, 104, 023701 (2014)

Naoto Inoue, Eisuke Takai, Tsutomu Arakawa, and Kentaro, Arginine and Lysine Reduce the High Viscosity of Serum Albumin Solutions for Pharmaceutical Injection, J. Biosci. Bioeng. 117, 539-543 (2014)

Katsuyoshi Aoki, Kentaro Shiraki, and Toshiaki Hattori. Observation of salt effects on hydration water of lysozyme in aqueous solution using terahertz time-domain spectroscopy. Applied Physics Letters. 103, 173704 (2013)

Naohisa Sugimoto Yasuaki Takakura, Kentaro Shiraki, Shinya Honda, Naoki Takaya, Takayuki Hoshino, and Akira Nakamura. Directed Evolution for Thermostabilization of a Hygromycin B Photphotransferase from Streptomyces hygroscopicus. Bioscience, Biotechnology, and Biochemistry 77, 2234-2241 (2013)

Shunsuke Tomita, Yumiko Tanabe, and Kentaro Shiraki. Oligoethylene glycols prevent thermal aggregation of alpha-chymotrypsin in a temperature-dependent manner: implications for design guidelines. Biotechnol. Prog. 29, 1325-1330 (2013)

Eisuke Takai, Shunsuke Yoshizawa, Daisuke Ejima, Tsutomu Arakawa, and Kentaro Shiraki. Synergistic Solubilization of Porcine Myosin in Physiological Salt Solution by Arginine. Int. J. Biological Macromolecules. 62, 647-651 (2013)

Atsushi Hirano, Tomoshi Kameda, Daisuke Shinozaki, Tsutomu Arakawa, Kentaro Shiraki. Molecular Dynamics Simulation of Arginine-Assisted Solubilization of Caffeic Acid: Intervention in the Interaction. J. Phys. Chem. B 117, 7518-7528 (2013)

Yui Shikiya, Shunsuke Tomita, Tsutomu Arakawa, and Kentaro Shiraki. Arginine inhibits proteins adsorption on polystyrene surface. PLoS One 8(8): e70762 (2013)

Shunsuke Tomita, Yukio Nagasaki, and Kentaro Shiraki. Different mechanisms of action of poly(ethylene glycol) and arginine on thermal inactivation of proteins. Biotechnology and Bioengineering, 109, 2543-2542 (2012)

Hiroki Yoshikawa, Atsushi Hirano, Tsutomu Arakawa, and Kentaro Shiraki. Effects of alcohol on the solubility and structure of native and disulfide-modified bovine serum albumin. Int. J. Biological Macromolecules 50, 1286-1291 (2012)

Atsushi Hirano, Hiroki Yoshikawa, Shuhei Matsushita, Yoichi Yamada, and Kentaro Shiraki. Adsorption and disruption of lipid bilayers by nanoscale protein aggregates. Langmure 28, 3887-3895 (2012)

Takaaki Kurinomaru, Shunsuke Tomita, Shinpei Kudo, Sumon Ganguli, Yukio Nagasaki, and Kentaro Shiraki. Improved Complementary Polymer Pair System: Switching for Enzyme Activity by PEGylated Polymers. Langmuir 28, 4334-4338 (2012)

Len Ito, Masaki Okumura, Kohsaku Tao, Yusuke Kasai, Shunsuke Tomita, Akiko Oosuka, Hidetoshi Yamada, Tomohisa Shibano, Kentaro Shiraki, Takashi Kumasaka, Hiroshi Yamaguchi. Glutathione ethylester, a novel protein refolding reagent, enhances both the efficiency of refolding and correct disulfide formation. Protein J. 31, 499-503 (2012)

Hiroki Yoshikawa, Atsushi Hirano, Tsutomu Arakawa, and Kentaro Shiraki. Mechanistic insights into protein precipitation by alcohol. Int. J. Biological Macromolecules 50, 865-871 (2012)

Tsutomu Arakawa, Atsushi Hirano, Kentaro Shiraki, Takako Niikura and Yoshiko Kita. Advances in characterization of neuroprotective peptide, Humanin. Curr. Med. Chem. 18, 5554-5563 (2011)

Atsushi Hirano, Kentaro Shiraki, and Tsutomu Arakawa. Polyethylene glycol behaves like weak organic solvent. Biopolymers, 97, 117-122 (2012)

Eisuke Takai, Katsuhisa Kitano, Junpei Kuwabara, Kentaro Shiraki. Protein Inactivation by Low-Temperature Atmospheric Pressure Plasma in Aqueous Solution. Plasma Processes and Polymers, 9, 77-82 (2012)

Ryosuke Ariki, Atsushi Hirano, Tsutomu Arakawa, Kentaro Shiraki. Drug solubilization effect of lauroyl-L-glutamate. J. Biochemistry, 151, 27-33 (2012)

Shunsuke Tomita and Kentaro Shiraki. Poly(acrylic acid) is a common non-competitive inhibitor for cationic enzymes with high affinity and reversibility. Journal of Polymer Science Part A: Polymer Chemistry. 49, 3835-3841 (2011)

Shunsuke Tomita, Hiroki Yoshikawa, and Kentaro Shiraki. Arginine controls heat-induced cluster-cluster aggregation of lysozyme at around the isoelectric point. Biopolymers, 95, 695-701 (2011)

Tsutomu Arakawa, Yoshiko Kita, Kentaro Shiraki and Satoshi Ohtake. The mechanism of protein precipitation by salts, polymers and organic solvents. Global J. Anal. Chem. 2, 152-167 (2011)

Shunsuke Tomita and Kentaro Shiraki. Why do solution additives suppress the heat-induced inactivation of proteins? Biotechnol. Prog., 27, 855-862 (2011).

Eisuke Takai, Atsushi Hirano, and Kentaro Shiraki. Effects of alkyl chain length of gallate on self-association and membrane-binding. J Biochemistry 150, 165-171 (2011)

Kiyouhisa Ohnishi, Kumiko Nakahira, Satoru Unzai, Kouta Mayanagi, Hiroshi Hashimoto, Kenataro Shiraki, Takeshi Honda and Itaru Yanagihara. Relationship between heat-induced fibrillogenicity and hemolytic activity of thermostable direct hemolysin and a related hemolysin of Vibrio parahaemolyticus. FEMS Microbiology Letters 318, 10-17 (2011)

Ryosuke Ariki, Atsushi Hirano, Tsutomu Arakawa, Kentaro Shiraki. Arginine increases solubility of alkyl gallates through interaction with the aromatic ring. J. Biochemistry149, 389-394 (2011)

Len Ito, Kentaro Shiraki, Takanori Matsuura, Masaki Okumura, Kazuya Hasegawa, Seiki Baba, Hiroshi Yamaguchi, and Takashi Kumasaka. High-resolution X-ray analysis revealing binding of arginine to aromatic residues of lysozyme surface: Implication of suppression of protein aggregation by arginine, Protein Engineering Design and Selection, 24, 269-274 (2011)

Atsushi Hirano, Kentaro Shiraki, Takako Niikura, Tsutomu Arakawa and Yoshiko Kita. Structure of three Humanin peptides with different activities upon interaction with liposome. Int. J. Biological Macromolecules. 48, 360-363 (2011)

Len Ito, Kentaro Shiraki, Masatomo Makino, Kazuya Hasegawa, and Takashi Kumasaka. Glycine amide shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation. FEBS letters 585, 550-560 (2011)

Atsushi Hirano, Ken Uda, Yutaka Maeda, Takeshi Akasaka, and Kentaro Shiraki. One-Dimensional Protein-Based Nanoparticles Induce Lipid Bilayer Disruption: Carbon Nanotube Conjugates and Amyloid Fibrils. Langmuir, 26, 17256-17259 (2010)

Atsushi Hirano, Yutaka Maeda, Xiaofei Yuan, Ryuuichi Ueki, Yosuke Miyazawa, Jun-ichi Fujita, Takeshi Akasaka, and Kentaro Shiraki. Controlled dispersion and purification of protein-CNT conjugates by guanidine hydrochloride. Chemistry, 16, 12221-12228 (2010)

Len Ito, Kentaro Shiraki, Tatsuya Uchida, Masaki Okumura and Hiroshi Yamaguchi. Crystallization and preliminary crystallographic analysis of the Achromobacter Protease I mutants. Acta Crystallographica Section F, 66, 1531-1532 (2010)

Kentaro Shiraki, Atsushi Hirano, Yoshiko Kita, A. Hajime Koyama and Tsutomu Arakawa. Potential application of arginine in interaction analysis. Drug Discoveries and Therapeutics, review, 4, 326-333 (2010)

Atsushi Hirano, Tomoshi Kameda, Tsutomu Arakawa, Kentaro Shiraki. Arginine-Assisted Solubilization System for Drug Substances: Solubility Experiment and Simulation. J. Phys. Chem. B, 114, 13455-13462 (2010)

Sumon Ganguli, Keitaro Yoshimoto, Shunsuke Tomita, Hiroshi Sakuma, Tsuneyoshi Matsuoka, Kentaro Shiraki, and Yukio Nagasaki "Improving the Heat Resistance of Ribonuclease A by the Addition of Poly(N,N-diethylaminoethyl methacrylate)-graft-poly(ethylene glycol) (PEAMA-g-PEG)" Macromolecular Bioscience, 10, 853-859 (2010)

Atsushi Hirano, Yutaka Maeda, Takeshi Akasaka, and Kentaro Shiraki. Mechanism of enhanced dispersion of single-walled carbon nanotubes with proteins by alcohols and chaotropes. Japanese Journal of Applied Physics, 49, 06GJ10 (2010)

Shunsuke Tomita, Len Ito, Hiroshi Yamaguchi, Gen-ichi Konishi, Yukio Nagasaki, and Kentaro Shiraki. Enzyme switch by complementary polymer pair system (CPPS). Soft Matter 6, 5320-5326 (2010)

Len Ito, Kentaro Shiraki and Hiroshi Yamaguchi. Comparative analysis of amino acids and amino-acid derivatives in protein crystallization. Acta Cryst. F66, 744-749 (2010)

Len Ito, Kentaro Shiraki and Hiroshi Yamaguchi. Amino acids and glycine ethyl ester as new crystallization reagents for lysozyme. Acta Cryst. F66, 750-754 (2010)

Yoshihiro Fujiwara, Yasuhiko Aiki, Lijun Yang, Fumio Takaiwa, Akemi Kosaka, Noriko M. Tsuji, Kentaro Shiraki, and Kenji Sekikawa. Extraction and purification of human interleukin-10 from transgenic rice seeds. Protein Expression and Purification, 72, 125-130 (2010).

Atsushi Hirano, Hiroko Tokunaga, Masao Tokunaga, Tsutomu Arakawa, and Kentaro Shiraki. The solubility of nucleobases in aqueous arginine solutions. Archives of Biochemistry and Biophysics. 497, 90-96 (2010)

Akiko Fujimoto, Atsushi Hirano, and Kentaro Shiraki. Ternary system of solution additives with arginine and salt for refolding of beta-galactosidase. Protein J. 29, 161-166 (2010)

Kentaro Shiraki and Soichiro Kayano. Thermal-assisted refolding: Dilution Folding Initiated at High Temperature. Curr. Pharm. Biotechnol. 11, 306-308 (2010)

Atsushi Hirano, Kentaro Shiraki, Takako Niikura, Tsutomu Arakawa and Yoshiko Kita. Structure changes of natively disordered Humanin in the presence of lipid. International Journal of Biometrics. (2010)

Kazutoshi Yasui, Masamichi Uegaki, Kentaro Shiraki, and Takeshi Ishimizu. Enhanced solubilization of membrane proteins by alkylamines and polyamines. Protein Science. 19, 486-493 (2010)

Tsutomu Arakawa, Atsushi Hirano, Kentaro Shiraki, Yoshiko Kita and A. Hajime Koyama. Stabilizing and destabilizing effects of arginine on deoxyribonucleic acid. Int. J. Biological Macromolecules. 46, 217-222 (2010)

国際特許　PTC/JP2018/027771

医療用タンパク質の複合体。特願2017-142905（テルモ株式会社、筑波大学）

医療用タンパク質の複合体。特願2016-205236（テルモ株式会社、筑波大学）

振とうストレス耐性を有するタンパク質水性懸濁剤。特願2014-219536 （テルモ株式会社）

ケラチンの熱凝集抑制剤。特願2014-254301（株式会社MILBON）

Protein aqueous suspension preparation. PCT/JP2014/78667（テルモ株式会社）

耐熱性を有するタンパク質水性懸濁剤。特願2013-223774（テルモ株式会社）

振とうストレス耐性を有するタンパク質水性懸濁剤。特願2013-223775（テルモ株式会社）

耐酸化性を有するタンパク質水性懸濁剤。特願2013-223778（テルモ株式会社）

凝集抑制性を有するタンパク質水性懸濁剤。特願2013-223779（テルモ株式会社）

流動性を有するタンパク質水性懸濁剤。特願2013-223780（テルモ株式会社）

特許第6179939（高濃度γグロブリン製剤の粘度低下方法）

特許5224515号（タンパク質を使うナノチューブの分散方法）

特許5120852号（ニトリルヒドラターゼ成熟化方法）

特許5119545号（溶液タンパク質の安定化方法）

水系媒体中へのカーボンナノチューブの分散方法、および分散させたカーボンナノチューブの精製方法。特願2010-188625（筑波大学）

特許5224515号（水系媒体中へのカーボンナノチューブの分散方法）

βアミロイド線維生成阻害剤。特願2009-245387（筑波大学）

水系溶媒中へのカーボンナノチューブの分散方法。特願2008-207851（筑波大学）

蛋白質の安定化のための温度応答性ポリマーの使用。特願2008-56460（筑波大学）

特許3976257号（溶液タンパク質の安定化方法）

白木賢太郎「天然にはない酵素の完全設計へ」現代化学2025年10月

白木賢太郎「巻頭言　AlphaFoldと人類の世紀」ニューサポート高校「理科」vol.44（2025年 秋号）

白木賢太郎「液-液相分離」脳科学辞典　2025年3月

白木賢太郎「相分離生物学の冒険」みすず書房 2023年2月

白木賢太郎「アミノ酸溶液とタンパク質溶液の基本的な性質」相分離解析プロトコール（羊土社） 2022年7月

白木賢太郎「低分子を利用するタンパク質溶液の粘度の制御法」バイオサイエンスとインダストリー2022年1月

白木賢太郎「タンパク質溶液から生命をイメージする」現代化学・50周年記念号・2021年4月

白木賢太郎「相分離生物学で考える創薬の視点」『MEDCHEM NEWS』2020年11月

白木賢太郎編『相分離生物学の全貌』東京化学同人 2020年11月

白木賢太郎「相分離生物学2020」現代科学2020年10月号

白木賢太郎「タンパク質の凝集と液-液相分離への添加剤の効果」生物工学会誌, vol 98, no 5,  (2020)

西奈美卓、白木賢太郎「相分離生物学で理解するプリオンの存在意義」物理学会誌 vol 75, no 4, 192-201 (2020)

浦 朋人、白木賢太郎（解説）「液 - 液相分離による酵素連続反応　細胞内にある代謝の理解」『実験医学』羊土社　vol 37, 3083-3088 (2019)

白木賢太郎、森英一朗、吉澤拓也（対談）「相分離生物学の誕生」現代化学2019年9月号

白木賢太郎『相分離生物学』東京化学同人 2019年8月

白木賢太郎（解説）「ゲノム編集」高校理科通信（第1号）東京書籍

白木賢太郎（解説）「相分離生物学 〜液-液相分離が解き明かす生命の謎〜」現代化学 572, 40-47 (2018)

白木賢太郎、岩下和輝、三村真大 『タンパク質の凝集と溶解性―基礎研究からバイオ産業・創薬研究への応用まで―』「タンパク質の共凝集と相分離」シーエムシー出版

白木賢太郎（解説）「構造を持たずに相互作用する天然変性タンパク質」

岩下和輝、亀田倫史、白木賢太郎。カーボンナノチューブとタンパク質の相互作用。生物工学会誌, vol 95, 723-725 (2017)

『改訂・生物』東京書籍（分担）

『スタンダード生物』東京書籍（分担）

白木賢太郎（解説）「タンパク質研究に活躍するアルギニン溶液」現代化学 555, 25-27 (2017)

白木賢太郎（解説）「ATPは疎水性分子を溶かす？」現代化学

『改訂・新編生物基礎』東京書籍（分担）

『改訂・生物基礎』東京書籍（分担）

白木賢太郎（解説）「アルツハイマー病患者は「思い出せない」」現代化学

白木賢太郎（解説）「アクティブマター」現代化学

白木賢太郎（解説）「進歩を遂げるクライオ電子顕微鏡」現代化学

白木賢太郎（解説）「白内障を点眼で治療する」現代化学

白木賢太郎（解説）「ガスを補足する多孔性の液体」現代化学

白木賢太郎（解説）「レトロウイルスとALS」現代化学

白木賢太郎（解説）「アルツハイマー病が感染する可能性」現代化学

白木賢太郎（解説）「メッシュで作るDNAオリガミ」現代化学

白木賢太郎（解説）「地球のリズムを刻むタンパク質の構造」現代化学

白木賢太郎（解説）「メンデルの法則を操作するクリスパー」現代化学

栗之丸隆章 、白木賢太郎「タンパク質沈殿-再溶解法による高濃度タンパク質医薬品の調製」『化学と生物』2015年5月号

白木賢太郎「高濃度タンパク質溶液の理解と会合・凝集・溶解の制御」生物工学特集号（企画・編集）2015年5月号

吉澤俊祐 、白木賢太郎「タンパク質の凝集剤としての塩・有機溶媒・高分子」生物工学、2015年5月号

白木賢太郎（解説）「DNAオリガミからアミロイドを伸ばす」現代化学・Flash 2014.10

白木賢太郎（解説）「６レターコードを持つ人工生物」現代化学・Flash 2014.9

白木賢太郎（解説）「クリスパーが生命科学・医療にもたらす衝撃」現代化学・2014.8

白木賢太郎（解説）「人工塩基対を持つ生物」現代化学・Flash 2014.8

白木賢太郎（解説）「酵母染色体の人工合成」現代化学Flash 2014.6

白木賢太郎、岩下和輝「タンパク質の凝集：モデルと測定法」『微粒子分散・凝集ハンドブック』シーエムシー出版

白木賢太郎（解説）「細胞内のタンパク質フォールディング」現代化学 2014.3

白木賢太郎（解説）「RNAの第二の情報」現代化学Flash 2014.5

白木賢太郎（解説）「始原細胞を作る」現代化学 2014.1

白木賢太郎「タマネギと涙」現代化学2013.12月号

平野篤、白木賢太郎（分担執筆）「姿をかえるタンパク質」『生物工学基礎講座　バイオよもやま話』日本生物工学会 p46-51 (2013)

白木賢太郎「巨大な輪っかをしたRNAの働き」 現代化学 No. 506, 11 (2013)

白木賢太郎「タンパク質折り紙」現代化学 2013.7

井上直人、白木賢太郎「難水溶性分子の溶解性を改善するアルギニン」Bioindustury, vol. 30, 22-28 (2013)

栗之丸隆章、白木賢太郎「高分子電解質をトリガーに用いる酵素機能の制御：トグルスイッチと超活性化」Bioscience & Industry vol. 71, 318-321 (2013)

白木賢太郎「天然変性タンパク質・構造と機能の新しい概念」現代化学2012.10月号

白木賢太郎「進展する合成生物学・人工生物の萌芽」現代化学2012.9月号

白木賢太郎「タンパク質の凝集しやすさを網羅」現代化学2012.8月号

白木賢太郎「人工細胞の増殖法」現代化学2011.12月号

平野篤、白木賢太郎「姿をかえるタンパク質」生物工学, 89, 404-407 (2011).

冨田峻介、白木賢太郎「タンパク質の劣化を抑制する溶液添加剤：非共有結合的な凝集と共有結合的な修飾」Journal of Japanese Society for Extremophiles, 9, 81-89 (2010).

白木賢太郎「リフォールディング液のデザイン」『酵素利用技術大系』小宮山真監修（分担執筆）

白木賢太郎「タンパク質フォールディング」東京書籍高校生物II　指導書 p15-17, 2010

白木 賢太郎『ニューサポート高校理科』 2010春号「タンパク質溶液学」, 2010

『生物科学入門』東京化学同人

『生命の謎は「タンパク質」で読み解ける！』メディアファクトリー

白木 賢太郎、伊藤 廉、山口 宏. タンパク質溶液のデザイン法. BioIndustry vol. 25, No. 5 (2008)

白木賢太郎「タンパク質は簡単にオリゴマー化する」『現代化学』Flash 2008.4

白木賢太郎「分子会合の新しい設計戦略-エントロピーに注目する分子設計」『現代化学』Flash 2008.3