Alertas
>> E-cigarette: Safety Communication - Related to Seizures Reported Following E-cigarette Use, Particularly in Youth and Young Adults...
>> Fluoroquinolone Antibiotics: Safety Communication - Increased Risk of Ruptures or Tears in the Aorta Blood Vessel in Certain Patients...
>> Cilest - Anticonceptivo - 2 lotes retirados del mercado por problemas de fabricación - Las personas que los consumen deben revisar si actualmente están tomando la medicación de esos lotes...
>> Azitromicina y aumento de la mortalidad por arrítmias graves...
>> Omeprazol y otros inhibidores bomba protones... aumento riesgo diarrea asociada a Clostridium difficile...
>> Aún no certezas... IRSS e hipertensión pulmonar persistente en recién nacidos...
>> Anticonceptivos y trombosis venosa... Alto riesgo con drospirenona...
>> Propoxifeno y toxicidad cardíaca grave en dosis terapéuticas... Retiro del mercado (U.S.) ...
>> Rosiglitazona y eventos cardiovasculares graves...
>> Lamotrigina y ocurrencia de meningitis aséptica...
>> Metoclopramida y diskinesia tardía...
>> Antipsicóticos y aumento mortalidad...
>> Riesgo de severa hepatotoxicidad con Diclofenac Gel 1%, uso tópico...
>> Antiepilépticos y aumento riesgo de suicidios...
>> Posible aumento de riesgo de fracturas con Inhibidores bomba de protones...
>> Tamiflu en menores de 1 año... en caso de emergencia...
>> Tiotropium y otros anticolinérgicos inhalados y aumento del riesgo de eventos cardiovasculares...
Más:
...(ACE inhibitors) drug during the first trimester of pregnancy had an increased risk of major congenital malformations, compared with... — Ks: IECA; enalapril; embarazo
...(carbidopa/levodopa and entacapone): Ongoing Safety Review: Possible increased cardiovascular risk — Ks: levodopa, carbidopa, entacapone, posible aumento riesgo cardiovascular, eventos mayores
...(dolasetron mesylate) ...torsade de pointes, an abnormal heart rhythm, which in some cases can be fatal. — Ks: dolasetron, nauseas, vómitos, antieméticos, arritmia ventricular grave, mortalidad, taquicardia ventricular, oncología, cancer.
... acute liver failure leading to liver transplant in patients treated with the heart medication dronedarone... — Ks: dronedarona, antiarrítmicos, toxicidad, aumento de mortalidad, insuficiencia hepática severa, hepatotoxicidad, transplante hepático
... increased risk of severe exacerbation of asthma symptoms, leading to hospitalizations in pediatric and adult patients as well as death in some patients using LABAs for the treatment of asthma... — Ks: salmeterol, formoterol, arformoterol, agonistas beta de larga acción, asma, niños, adolescentes, adultos, actualización de indicaciones, contraindicaciones, reacciones adversas, eventos adversos graves, uso no-racional
... oral anti-viral drug for the treatment of uncomplicated influenza in patients one year and older whose flu symptoms have not lasted more than two days... — Ks: Tamiflu; oseltamivir phosphate; gripe
... pioglitazone: Ongoing Safety Review - Potential Increased Risk of Bladder Cancer... — Ks: pioglitazona, cancer, diabetes, DBT
... progressive multifocal leukoencephalopathy (PML), a rare brain infection, in patients using the psoriasis drug Raptiva (efalizumab). — Ks: efalizumab; psoriasis; LMP
... proton pump inhibitors (PPIs) may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD)... develop diarrhea that does not improve. — Ks: Inhibidores bomba de protones, omeprazol, pantoprazol, lanzoprazol, rabeprazol esomeprazol, dexlanzoprazol y otros; diarrea, Clostridium defficile
... risk for mortality and/or cardiovascular events in patients who received tiotropium or inhaled anticholinergics... — Ks: tiotropium; anticolinérgicos inhalatorios; ipratropium
...should re-evaluate the need for starting or continuing treatment with a PPIs (proton pump inhibitors) — Ks: omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole; clopidogrel
... when propoxyphene was taken at therapeutic doses, there were significant changes to the electrical activity of the heart: prolonged PR interval, widened QRS complex and prolonged QT interval... — Ks: propoxifeno, dextropropoxifeno, toxicidad cardíaca grave en dosis terapéuticas, arritmias; opioides, analgésicos; retiro, dolor.
... will significantly restrict the use of the diabetes drug Avandia (rosiglitazone) to patients with Type 2 diabetes who cannot control their diabetes on other medications... — Ks: rosiglitazona, gitazonas, diabetes, DBT, eventos cardiovasculares graves, stroke, pioglitazona
Acetaminophen Prescription Products Limited to 325 mg Per Dosage Unit: Drug Safety Communication — Ks: injuria hepática severa, reacciones alergicas; interacción con opioides, alcohol etílico, hepatotoxicidad grave; uso combinado con opioides por via oral y riesgo aumentado de RAD; dosis máximas de paracetamol 4 gr/dia en adultos.
a condition referred to as heparin-induced thrombocytopenia and thrombosis (HITT)... — Ks: heparina; trombosis
Angiotensin Receptor Blockers (ARBs): Ongoing Safety Review for Cancer Risk — Ks: antagonistas del receptor de angiotensina, sartanes, hipertensión arterial, riego de cancer
Antidepressant Use in Children, Adolescents, and Adults — Ks: antidepresivos; suicidios; adolescentes
antiepileptic drugs had approximately twice the risk of suicidal behavior or ideation... — Ks: antiepilépticos; suicidios
antipsychotics are associated with an increased risk of mortality... — Ks: antipsicóticos; mortalidad
Aspirin for the prevention of cardiovascular disease: clinical summary of a U.S. Preventive Services Task Force — Recommendation Summary (2009). The U.S. Preventive Services Task Force (USPSTF)._____________________Ks: aspirina; prevención; riesgo cardiovascular; Stroke
azithromycin can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm. Patients at particular risk for developing this condition include those with known risk factors such as existing QT interval prolongation, low blood levels of potassium or magnesium, a slower than normal heart rate, or use of certain drugs used to treat abnormal heart rhythms, or arrhythmias... — KS: Azitromicin, macrólidos, antibióticos, riesgo cardiovascular, arritmias, levofloxacin, aumento mortalidad
Bisphosphonates... risk of atypical fractures of the thigh, known as subtrochanteric and diaphyseal femur fractures.. — Ks: bifosfonatos, osteoporosis, fracturas atípicas, riesgos.
Chronic use of metoclopramide has been linked to tardive dyskinesia... — Ks: metoclopramida; diskinesia
Concomitant Use of Ibuprofen and Aspirin — Ks: aspirina; ibuprofeno
Desipramine... extreme caution should be used when this drug is given to patients who have a family history of sudden death, cardiac dysrhythmias, and cardiac conduction disturbances... — Ks: desipramina, antidepresivos; historia familiar, arritmias, muerte súbita, convulsiones.
Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture... — Ks: quinolonas; ciprofloxacina
higher frequency of suicidal behavior in young adults treated with paroxetine compared with placebo... — Ks: antidepresivos; suicidios
higher risk of blood clots in women taking birth control pills containing the progestin drospirenone... — Ks: progestinas, progestagenos, trombisis venosa, embolia, anticonceptivos, drospirenona, levonorgestrel.
higher risk of heart attack in patients infected with HIV-1 who were taking Ziagen (abacavir) or Videx (didanosine) as part of their drug therapy... — Ks: abacavir; didanosin
increased risk of rhabdomyolysis when amiodarone is taken with simvastatin... — Ks: amiodarona; sinvastatina; estatinas; rabdomiólisis
increased risk of serious skin reactions including Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) from phenytoin therapy in Asian patients... — Ks: fenitoina; difenilhidantoina
interaction of ceftriaxone with calcium-containing products based on reports of fatal cases in neonates — Ks: ceftriaxona; neonatos; pediatría
Lamictal (lamotrigine): Label Change - Risk of Aseptic Meningitis — Ks: lamotrigina, meningitis aséptica, reacciones adversas, epilepsia, anticonvulsivos, antiepilépticos, niños, adultos
Local Anesthetics, Continuously Infused (marketed as bupivacaine, chlorprocaine, lidocaine, mepivacaine, procaine, ropivacaine) - Chondrolysis — Ks: lidocaina, procaina, mepivacaina, bupivacaina, ropivacaina, cloroprocaina; condrólisis, toxicidad articular, vía intraarticular; dolor postquirúrgico.
multi-center European study was designed to evaluate the safety of Innohep (tinzaparin), a low-molecular-weight heparin, compared to unfractionated heparin... — Ks: heparina de bajo peso molecular
Natalizumab. FDA continues to receive reports of progressive multifocal leukoencephalopathy (PML) in patients receiving Tysabri. — Ks: esclerosis múltiple; enfermedad de Crohn activa severa; leucoencefalopatía multifocal progresiva.
Nimodipine... When administered intravenously or parenterally, it can cause serious adverse events, including death. — Ks: nimodipina; eventos adversos; mortalidad
proton pump inhibitors... possible increased risk of fractures of the hip, wrist, and spine... — Ks: omeprazol, pantoprazol, otros inhibidores bomba protones, riesgo fracturas, cadera, muñeca, columna
Sibutramine: Market Withdrawal Due to Risk of Serious Cardiovascular Events — Ks: Sibutramina, muerte súbita, paro cardíaco, stroke, toxicidad cardiovascular grave; tratamiento de obesidad, perdida de peso.
Suicidal Behavior and Ideation and Antiepileptic Drugs — The FDA has completed its analysis of reports of suicidality ... This observation suggests that the risk applies to all antiepileptic drugs used for any indication.
Valproate Sodium and related products (valproic acid and divalproex sodium): Risk of Birth Defects — Ks: embarazo; valproato, acido valproico, divalproex; obstetricia, neurología, psiquiatría; malformaciones, defectos congénitos, alto riesgo; epilepsia, migraña.
valproate sodium or related products (valproic acid and divalproex sodium) during pregnancy > an increased risk of lower cognitive test scores... — Ks: embarazo, antiepilépticos, anticonvulsivos, desorden bipolar, migraña, niños expuestos en útero, trastornos cognitivos, test, inteligencia
Voltaren Gel (diclofenac sodium topical gel) 1% - Hepatic Effects — Ks: diclofenac; vía tópica, gel; toxicidad hepática severa, hepatitis fulminante, insuficiencia; transplante hepático.