2022年度

1. A novel application of hectorite nanoclay for preparation of colorectal cancer spheroids with malignant potential.

Hirade Y, Kubota M, Kitae K, Yamamoto H, Omori H, Shinoki S, Ohmura T, Tsujikawa K.

Lab Chip. 2023;23(4):609-623. 

2. Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.

Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, Hashimoto R, Shigesada N, Takahashi J, Tachibana M, Tanaka S, Obana M, Hino N, Ikawa M, Tsujikawa K, Ono C, Matsuura Y, Kidoya H, Takakura N, Kubota Y, Doi T, Takayama K, Yoshioka Y, Fujio Y, Okada Y.

Proc Natl Acad Sci U S A. 2023;120(3):e2213317120. 

3. Circulating extracellular vesicles carrying Firmicutes reflective of the local immune status may predict clinical response to pembrolizumab in urothelial carcinoma patients

Jingushi K, Kawashima A, Saito T, Kanazawa T, Motooka D, Kimura T, Mita M, Yamamoto A, Uemura T, Yamamichi G, Okada K, Tomiyama E, Koh Y, Matsushita M, Kato T, Hatano K, Uemura M, Tsujikawa K, Wada H, Nonomura N.

Cancer Immunol Immunother. 2022;71(12):2999-3011

4. Clinical significance of ALKBH4 expression in non-small cell lung cancer.

Aoki M, Ueda K, Kamimura G, Iwamoto Y, Ikehata M, Tabata K, Sakagami Y, Morizono S, Tokunaga T, Umehara T, Harada-Takeda A, Maeda K, Nagata T, Kariatsumari K, Furukawa T, Tsujikawa K, Sato M.

Transl Cancer Res. 2022 Jul;11(7):2040-2049. 

5. Safety evaluation of MA-T after ingestion in mice.

Noguchi T, Tachibana K, Inoue T, Sakai T, Tsujikawa K, Fujio Y, Yamagishi Y, Hamaguchi S, Kutsuna S, Kondoh M.

Toxicology. 2022;477:153254. 

6. High-fat diet promotes prostate cancer growth through histamine signaling.

Matsushita M, Fujita K, Hatano K, Hayashi T, Kayama H, Motooka D, Hase H, Yamamoto A, Uemura T, Yamamichi G, Tomiyama E, Koh Y, Kato T, Kawashima A, Uemura M, Nojima S, Imamura R, Mubeen A, Netto GJ, Tsujikawa K, Nakamura S, Takeda K, Morii E, Nonomura N.

Int J Cancer. 2022;151(4):623-636.

7. Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

Hori M, Saito Y, Matozaki T, Maehara K, Ohkawa Y, Potente M, Watanabe S, Braun T, Uezumi A, Fukada SI.

Cell Stem Cell. 2022;29(2):265-280.e6. 

8. Discovery of two novel ALKBH5 selective inhibitors that exhibit uncompetitive or competitive type and suppress the growth activity of glioblastoma multiforme

Takahashi H, Hase H, Yoshida T, Tashiro J, Hirade Y, Kitae K, Tsujikawa K.

Chem Biol Drug Des. 2022;100(1):1-12