Endocrine disrupting pesticides

Developmental Exposure to Endocrine Disruptors and Male Urogenital Tract Malformations - Fernandez, M and Olea, N. 2012In a Gore, A (Ed) Endocrine Disruptors and Puberty (225-235). Humana Press

Endocrine disruption and cytotoxicity of glyphosate and roundup in human JAr cells in vitro. Integrative Pharmacology, Toxicology and Genotoxicology. - Young, F., Ho, D., Glynn, D., & Edwards, V.

Environmental Chemicals: Evaluating Low-Dose Effects - Linda S. BirnbaumDirector, NIEHS and NTP, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, Citation: Birnbaum LS 2012. Environmental Chemicals: Evaluating Low-Dose Effects. Environ Health Perspect 120:a143-a144. 

Executive Summary to The Endocrine Society’s 2nd Scientific Statement on EDCs - Endocrine Society

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. - A  team of researchers review two major concepts in EDC studies: low dose and nonmonotonicity. Low-dose effects were defined by the National Toxicology Program as those that occur in the range of human exposures or effects observed at doses below those used for traditional toxicological studies. Whether low doses of EDCs influence certain human disorders is no longer conjecture, because epidemiological studies show that environmental exposures to EDCs are associated with human diseases and disabilities. Authors conclude that when nonmonotonic dose-response curves occur, the effects of low doses cannot be predicted by the effects observed at high doses. Thus, fundamental changes in chemical testing and safety determination are needed to protect human health.[Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, et al. 2012. Endocr Rev.33(3):378-455.]

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses. - Laura N. Vandenberg, Theo Colborn, Tyrone B. Hayes, Jerrold J. Heindel, David R. Jacobs, Jr., Duk-Hee Lee, Toshi Shioda, Ana M. Soto, Frederick S. vom Saal, Wade V. Welshons, R. Thomas Zoeller, and John Peterson Myers; Endocrine Reviews, June 2012

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses - See more at: http://press.endocrine.org/doi/full/10.1210/er.2011-1050#sthash.o2z3SE1D.dpuf - Laura N. Vandenberg, Theo Colborn, Tyrone B. Hayes, Jerrold J. Heindel, David R. Jacobs, Jr., Duk-Hee Lee, Toshi Shioda, Ana M. Soto, Frederick S. vom Saal, Wade V. Welshons, R. Thomas Zoeller, and John Peterson Myers