Alzheimer's & Neurodegenerative

Cognitive impairment and increased Aβ levels induced by paraquat exposure are attenuated by enhanced removal of mitochondrial H2O2 - Liuji Chen, Si-Eun Yoo, Ren Na, Yuhong Liu, Qitao Ran, . published online 24 March 2011.

Elevated Serum Pesticide Levels and Risk for Alzheimer Disease - Jason R. Richardson, PhD1,2; Ananya Roy, ScD2; Stuart L. Shalat, ScD1,2; Richard T. von Stein, PhD2; Muhammad M. Hossain, PhD1,2; Brian Buckley, PhD2; Marla Gearing, PhD4; Allan I. Levey, MD, PhD3; Dwight C. German, PhD5

Neurodegenerative Diseases and Exposure to Pesticides in the Elderly; - results suggest the presence of neurologic impairments in elderly persons who were exposed occupationally to pesticides. [Baldi, I, et al. Am J Epidemiol 2003; 157:409-414.]

Occupational exposure to pesticides increases the risk of incident AD - [Hayden KM, et al. 2010. Neurology, May 11;74(19):1524-30]

Occupational risk factors in Alzheimer's disease: a review assessing the quality of published epidemiological studies - Eleven studies explored the relationship of AD with solvents, seven with EMF, six with pesticides, six with lead and three with aluminium. For pesticides, studies of greater quality and prospective design found increased and statistically significant associations.  [Santibáñez M, et al. 2007. Occup Environ Med. Nov;64(11):723-32. Epub 2007 May 24]

Risk factors for Alzheimer's disease: a population-based, longitudinal study in Manitoba, Canada - Occupational exposure to fumigants and/or defoliants was a significant risk factor for Alzheimer's disease [Tyas SL, et al. Int J Epidemiol. 2001 Jun;30(3):598-9]