Kidney/renal cancer

Cancer in offspring of parents engaged in agricultural activities in Norway: incidence and risk factors in the farm environment. - Parental agricultural exposure to pesticides is associated with Wilms’ tumor, as well as other forms of cancer. [Kristensen, P., et al. 1996. Int J Cancer 65(1):39-50.]

Childhood cancer and paternal employment in agriculture: the role of pesticides - Paternal occupational exposure to pesticides is statistically significant for kidney cancer, Wilms’ tumor in offspring. [Fear, N.T., et al. 1998. Br J Cancer 77(5):825-829.]

Long-term Toxicity of a Monsanto Roundup Herbicide and a Roundup-tolerant Genetically Modified Maize - Gilles-Eric Séralini1, Emilie Clair, Robin Mesnage, Steeve Gress, Nicolas Defarge, Manuela Malatesta, Didier Hennequin and Joël Spiroux de Vendômois. Male rats presented up to four times more large palpable tumors starting 600 days earlier than in the control group, in which only one tumor was noted. These results may be explained by not only the non-linear endocrine-disrupting effects of Roundup but also by the overexpression of the EPSPS transgene or other mutational effects in the GM maize and their metabolic consequences.

Renal cell carcinoma and occupational exposure to chemicals in Canada - An increased risk of renal cell carcinoma in males is associated with exposure to herbicides (1.6 OR) and pesticides (1.8 OR) and in particular a dose-response relationship for herbicides.  [Hu, J., et al. 2002. Occup Med 52(3):157-164.]

Risk of childhood cancers associated with residence in agriculturally intense areas in the United States. - Analyzes incidence data from U.S. children ages 0-14 years diagnosed with cancer between 1995 and 2001 and residence in a county with agricultural activity finds an elevated risk (OR 2.1) for Wilm’s tumors at high agricultural activity (greater than 60% of county acreage devoted to farming). [Carrozza, S.E., et al. 2008. Environ Health Perspect 116(4):559-565.]