Cancer in offspring of parents engaged in agricultural activities in Norway: incidence and risk factors in the farm environment. - In a large cohort study in Norway, parental occupational agricultural use of pesticides is associated with childhood brain tumors in farmer’s offspring aged 0-14 years .[Kristensen, P., et al. 1996. Int J Cancer 65(1):39-50]
Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes - Suggests that exposure in childhood to insecticides in combination with a reduced ability to detoxify them increases risk of developing brain tumors. [Nielsen, S.S., et al. 2010. Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes. Environmental Health Perspectives 118(1):144-149]
Exposure to pesticides and the risk of childhood brain tumors - suggest that preconception pesticide exposure, and possibly exposure during pregnancy, is associated with an increased CBT risk.Cancer Causes & Control, July 2013, Volume 24, Issue 7, pp 1269-1278; Kathryn R. Greenop et. Al
Farm and animal exposures and pediatric brain tumors: results from the United States West Coast Childhood Brain Tumor Study. - A National Cancer Institute study finds that mothers exposed to farm pesticides were more likely to have a child with a brain tumor.; [Holly, E.A., et al. 1998. Cancer Epidemiol Biomarkers Prev 7(9):797-802]
Farm-related exposures and childhood brain tumours in seven countries: results from the SEARCH International Brain Tumour Study. - Finds that maternal exposure, during the 5 years proceeding the child’s birth, is related to childhood brain tumors, relative to maternal exposure to agricultural pesticides.[Efird, J.T., et al. 2003. Paediatr Perinat Epidemiol 17(2):201-211]
Risk factors for astrocytic glioma and primitive neuroectodermal tumor of the brain in young children: a report from the Children's Cancer Group. - Finds elevated risks for primitive neuroectodermal tumor (PNET), one the of the most common subtypes of brain tumors in children, for mother’s residence on a farm during pregnancy and for the child’s residence on a farm for at least one year.. [Bunin, G.R., et al. 1994. Cancer Epidemiology, Biomarkers and Prevention 3:197-204]
The Upper Midwest Health Study: a case-control study of primary intracranial gliomas in farm and rural residents. - A NIOSH study finds moving to a farm between the ages of 11 and 20 is associated with a greater risk for gliomas. [Ruder, A.M., et al. 2006. J Agric Saf Health 12(4):255-274]