Lymphoma - Non-Hodgkin's

A case-control study of non-Hodgkin lymphoma and exposure to pesticides - Finds an increased risk for NHL for people exposed to herbicides, specifically significant is exposure to MCPA, and fungicides.[Hardell, L., et al. 1999. Cancer 85(6):1353-1360]

Agricultural pesticide use and risk of t(14;18)-defined subtypes of non-Hodgkin lymphoma. - Finds the risk of t(14;18)-positive NHL subtype is significantly elevated among farmers who used animal insecticides, crop insecticides, herbicides and fumigants . No increased risk of t(14;18)-negative NHL subtype for these pesticides, which may explain some of the inconsistencies in epidemiological study of NHL and pesticide exposure. Find risk increases with longer duration of use. [Chiu, B., et al. 2006. Blood 108(4):1363-1369]

Exposure to Glyphosate-Based Herbicides and Risk for Non-Hodgkin Lymphoma: A Meta-Analysis and Supporting Evidence - Luoping Zhang, Iemaan Ranaa, Rachel M.Shaffer, Emanuela Taioli, Lianne Sheppard

Farming, pesticide use and hairy-cell leukemia. - A significant association is found between HCL and exposure to pesticides used in farming . Orgaonphosphates were positively associated with HCL.[Clavel, J., et al. 1996. Scand J Work Environ Health 22(4):285-293]

Integrative assessment of multiple pesticides as risk factors for non-Hodgkin's lymphoma among men. - Finds coumaphos, diazinon, and glyphosate are associated with an increase in NHL incidence.[De Roos, A.J., et al. 2003. Occupational and Environmental Medicine 60(9):e11]

Non-Hodgkin's lymphoma and specific pesticide exposures in men: cross-Canada study of pesticides and health. - Finds an increase risk of NHL for exposure to dicamba, carbamates, OPs, amide fungicides and fumigant carbon tetrachloride, mecoprop, malathion and carbaryl. [McDuffie, H., et al. 2001.Cancer Epidemiology, Biomarkers & Prevention 10:1155-1163]

Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health Study. - Finds a significant increase in risk for NHL and lindane.[Purdue, M.P., et al. 2007. Int J Cancer 120(3):642-649]

Occupational exposure to pesticides and risk of hematopoietic cancers: meta-analysis of case-control studies. - finds that occupational pesticide exposure greater than ten years significantly increases risk of NHL (OR 1.65); [Merhi, M, et al. 2007. Cancer Causes Control 18(10):1209-1226]

Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study. - Shows a suggestive association between terbufos and NHL.[Bonner, M.R., et al. 2010. Cancer Causes Control 21(6):871-7]

Pesticide exposure as risk factor for non-Hodgkin lymphoma including histopathological subgroup analysis. - Finds the highest risk is for exposure to: herbicides – MCPA & glyphosate . Other lymphomas associated with exposure to phenoxyacetic acids phenoxy herbicides .[Eriksson, M., et al. 2008. Int J Cancer 123(7):1657-1663]

Proportionate mortality study of golf course superintendents. - Finds an elevated number deaths from NHL (PMR 237).[Kross, B.C., et al. 1996. Am J Ind Med 29(5):501-506]