研究業績（1990年〜1999年）
1999年
Norman J. Kennedy, Takao Kataoka, Jürg Tschopp, Ralph C. Budd
Caspase activation is required for T cell proliferation
Journal of Experimental Medicine, 190(12), 1891–1896 (1999)
Saori Yuuya, Hisahiro Hagiwara, Toshio Suzuki, Masayoshi Ando, Atsushi Yamada, Kouji Suda, Takao Kataoka, Kazuo Nagai
Guainolides as immunomodulators. Synthesis and biological activities of dehydrocostus lactone, mokko lactone, eremanthin, and their drivatives
Journal of Natural Products, 62(1), 22–30 (1999)
1998年
Takao Kataoka, Michael Schröter, Michael Hahne, Pascal Schneider, Martin Irmler, Margot Thome, Cristopher J. Froelich, Jürg Tschopp
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation
Journal of Immunology, 161(8), 3936–2942 (1998)
Michael Hahne, Takao Kataoka, Michael Schröter, Kay Hofmann, Martin Irmler, Jean-Luc Bodmer, Pascal Schneider, Tierry Bornand, Nils Holler, Lars E. French, Bernard Sordat, Donata Rimoldi, Jürg Tschopp
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth
Journal of Experimental Biology, 188(6), 1185–1190 (1998)
Tomohiko Sato, Hiroki Konno, Yasufumi Tanaka, Takao Kataoka, Kazuo Nagai, Harry H. Wasserman, Shoji OhkumaProdigiosins as a new group of H+/Cl- symporters that uncouple proton translocators
Journal of Biological Chemistry, 273(34), 21455–21462 (1998)
Shoji Okuma, Tomohiko Sato, Masayuki Okamoto, Hidekazu Matsuya, Kunizo Arai, Takao Kataoka, Kazuo Nagai, Harry H. Wasserman
Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport
Biochemical Journal, 334(Pt 3), 731–741 (1998)
Hiroki Konno, Hidekazu Matsuya, Masayuki Okamoto, Tomohiko Sato, Yasufumi Tanaka, Y Yokoyama, Takao Kataoka, Kazuo Nagai, Harry H. Wasserman, Shoji Okuma
Prodigiosins uncouple mitochondrial and bacterial F-ATPases: evidence for their H+/Cl- symport activity
Journal of Biochemistry, 124(3), 547–556 (1998)
Takao Ashikaga, Mariko Honma, Kazuko Munemura, Takao Kataoka, Toyoshige Endo, Makari Yamasaki, Junji Magae, Kazuo Nagai
Selective induction of interleukin-1 production and tumor killing activity of macrphages through apoptosis by the inhibition of oxidative respiration
Bioscience, Biotechnology, and Biochemistry, 62(6), 1115–1121 (1998)
Mi-Heon Lee, Masahiro Yamashita, Ryouhei F. Tsuji, Makari Yamasaki, Takao Kataoka, Junji Magae, Kazuo Nagai
Suppression of T cell stimulating function of allogeneic antigen presenting cells by prodigiosin 25-C
Journal of Antibiotics, 51(1), 92–94 (1998)
1997年
Takao Kataoka, Ken-ichi Togashi, Hajime Takayama, Kazuaki Takaku, Kazuo Nagai
Inactivaiton and proteolytic degradation of perforin within lytic granules upon neutralization of acidic pH
Immunology, 91(3), 493–500 (1997)
Pascal Schneider, Margot Thome, Kim Burns, Jean-Luc Bodmer, Kay Hofmann, Takao Kataoka, Nils Holler Jürg Tschopp
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB
Immunity, 7(6), 831–836 (1997)
Tetsuya Wakabayashi, Shigenari Hirokawa, Noriaki Yamauchi, Takao Kataoka, Je-Tae Woo, Kazuo Nagai
Immunomodulating activities of polysaccharide fractions from dried safflower petals
Cytotechnology, 25(1-3), 205–211 (1997)
Ken-ichi Togashi, Takao Kataoka, Kazuo Nagai
Concanamycin A, a vacular type H+-ATPase inhibitor, induces cell death in activated CD8+ CTL
Cytotechnology, 25(1-3), 127–135 (1997)
Shin-ichi Hamada, Takao Kataoka Je-Tae Woo, Atsushi Yamada, T Yoshida, Toshio Nishimura, Noboru Otake, Kazuo Nagai
Immunosuppressive effects of gallic acid and chebulagic acid on CTL-mediated cytotoxicity
Biological & pharmacological Bulletins, 20(9), 1017–1019 (1997)
Ken-ichi Togashi, Takao Kataoka, Kazuo Nagai
Characterization of a series of vacuolar type H+-ATPase inhibitors on CTL-mediated cytotoxicity
Immunology Letter, 55(3), 139–144 (1997)
Je-Tae Woo, Yasuo Ohba, Kahori Tagami, Koji Sumitani, Takao Kataoka, Kazuo Nagai
Prodigiosin 25-C and metacycloprodigiosin suppress the bone resorption by osteoclasts
Bioscience, Biotechnology, and Biochemistry, 61(2), 400–402 (1997)
片岡 孝夫、永井 和夫
細胞傷害顆粒の構造と機能
蛋白質 核酸 酵素, 42, 1238–1243 (1997) (review)
1996年
Takao Kataoka, Michihiko Sato, Shunzo Kondo, Kazuo Nagai
Estimation of pH and the number of lytic granules in a CD8+ CTL clone treated with an inhibitor of vacuolar H+-ATPase concanamycin A
Bioscience, Biotechnology, and Biochemistry, 60(10), 1729–1731 (1996)
Takao Kataoka, Nabukata Shinohara, Hajime Takayama, Kazuaki Takaku, Shunzo Kondo, Shin Yonehara, Kazuo Nagai
Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity
Journal of Immunology, 156(10), 3678–3686 (1996)
Tanapat Palaga, Takao Kataoka, Je-Tae Woo, Kazuo Nagai
Suppression of apoptotic cell death of IL-3-dependent cell lines by ER/SR Ca2+-ATPase inhibitors upon IL-3 deprivation
Experimental Cell Research, 228(1), 92–97 (1996)
Hidefumi Suzuki, Masahiro Yamashita, Joey C. Y. Lee, Takao Kataoka, Junji Magae, Kazuo Nagai
Immunosuppressive activity of streptonigrin in vitro and in vivo
Bioscience, Biotechnology, and Biochemistry, 60(5), 789–793 (1996)
Uichi Nishiyama, Makoto Ubukata, Junji Magae, Takao Kataoka, Ferenc Erdodi, David J. Hartshorne, Kiyoshi Isono, Kazuo Nagai, Hiroyuki Osada
Structure-activity relationship within a series of degradation products of tautomycin
Bioscience, Biotechnology, and Biochemistry, 60(1), 103–107 (1996)
1995年
Takao Kataoka, Makoto Muroi, Shoji Ohkuma, Takaki Waritani, Junji Magae, Akira Takatsuki, Shunzo Kondo, Makari Yamasaki, Kazuo Nagai
Prodigiosin 25-C uncouples vacuolar type H+-ATPase, inhibits vacuolar acidification and affects glycoprotein processing
FEBS Letters, 359(1), 53–59 (1995)
Takao Kataoka, Junji Magae, Makari Yamasaki, Kazuo Nagai
Prodigiosin 25-C perturbs permeation of acetate in a cultured cell line
Bioscience, Biotechnology, and Biochemistry, 59(10), 1891–1895 (1995)
Masatoshi Taniguichi, Takao Kataoka, Hidefumi Suzuki, Masatoshi Ando, Kei Arao, Junji Magae, Toshio Nishimura, Noboru Otake, Kazuo Nagai
Costunolide and dehydrocostus lactone as inhibitors of killing function of cytotoxic T lymphocytes
Bioscience, Biotechnology, and Biochemistry, 59(11), 2064–2067 (1995)
Noriki Watanabe, Takao Kataoka, Tatsuharu Tajika, Masakazu Uramoto, Junji Magae, Kazuo Nagai
1’-Acetoxychavicol acetate as an inhibitor of phagocytosis of macrophages
Bioscience, Biotechnology, and Biochemistry, 59(8), 1566–1567 (1995)
Mi-Heon Lee, Takao Kataoka, Junji Magae, Kazuo Nagai
Prodigiosin 25-C suppression of cytotoxic T cells in vitro and in vivo similar to that of concanamycin B, a specific inhibitor of vacuolar type H+-ATPase
Bioscience, Biotechnology, and Biochemistry, 59(8),1417–1421 (1995)
Ken-ichi Togashi, Junji Magae, Takao Kataoka, Kazuo Nagai
Thiol-protease inhibitors selectively inhibit presentation of antigen incorporated through B cell antigen receptors
Biochemical and Biophysical Research Communications, 210(2), 324–328 (1995)
1994年
Takao Kataoka, Kazuaki Takaku, Junji Magae, Nobukata Shinohara, Hajime Takaku, S Kondo, Kazuo Nagai
Acidification is essential for maintaining the structure and function of lytic granules of CTL. Effect of concanamycin A, an inhibitor of vacuolar type H+-ATPase, on CTL-mediated cytotoxicity
Journal of Immunology, 153(9), 3938–3947 (1994)
Junji Magae, Toshimi Nagi, Kazuaki Takaku, Takao Kataoka, Hiroyuki Koshino, Masakazu Uramoto, Kazuo Nagai
Screening for specific inhibitors of phagocytosis of thioglycollate-elicited macrophages
Bioscience, Biotechnology, and Biochemistry, 58(1), 104–107 (1994)
1993年
Takao Kataoka, Masaaki Wachi, Jun Nakamura, Shinyo Gayama, Makari Yamasaki, Kazuo Nagai
Fully methylated oriC with negative superhelicity forms an oriC-membrane complex before initiation of chromosome replication
Biochemical and Biophysical Research Communications, 194(3), 1420–1296 (1993)
Junji Magae, Ryouhei F. Tsuji, Zhang Wang, Takao Kataoka, Mi-Heon Leee, Tosihiko Hamada, Tomohiro Kurisaki, Masakazu Uramoto, Makari Yamasaki, Kazuo Nagai
Melastini, a novl pruduct of Streptomyces that selectively inhibits leukemia cell growth
Bioscience, Biotechnogy, and Biochemistry, 57(6), 969–972 (1993)
1992年
Takao Kataoka, Junji Magae, Kunihiro Kasamo, Hiroyasu Yamanishi, Akira Endo, Makari Yamasaki, Kazuo Nagai
Effects of prodigiosin 25-C on cultured cell lines: its similarity to monovalent polyether ionophores and vacuolar type H+-ATPase
Journal of Antibiotics, 45(10), 1618–1625 (1992)
Akihiro Kaidow, Takao Kataoka, Masaaki Wachi, Ayako Takada, Makari Yamasaki, Kazuo Nagai
The 55-kilodalton protien in an oriC complex fraction is glycogen syntase
Journal of Bacteriology, 174(16), 5454–5456 (1992)
Takao Kataoka, Junji Magae, Hideo Nariuchi, Makari Yamasaki, Kazuo Nagai
Enhancement by concanavalin A of the suppressive effect of prodigiosin 25-C on proliferation of murine splenocytes
Journal of Antibiotics, 45(8), 1303– 1312 (1992)
1991年
Takao Kataoka, Shinyo Gayama, Keigetsu Takahashi, Masaaki Wachi, Makari Yamasaki, Kazuo Nagai
Only oriC and its flanking region are recovered from the complex formed at the time of initiation of chromosome replication in Eshcerichia coli
Research in Mirobiology, 142(2-3), 155–159 (1991)
1990年
Shinyo Gayama, Takao Kataoka, Masaaki Wachi, Gakuzo Tamura, Kazuo Nagai
Periodic formation of the oriC complex of Esherichia coli
EMBO Journal, 9(11), 3761–3765 (1990)
Ryouhei F. Tsuji, Masakuni Yamamoto, Akito Nakamura, Takao Kataoka, Junji Magae, Kazuo Nagai, Makari Yamasaki
Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system
Journal of Antibiotics, 43(10), 1293–1301 (1990)