Ostruthin

ヒト肺がん腫A549細胞においてTNF-αで誘導されるICAM-1発現を阻害するが、細胞生存率の低下との選択性が低い。

【発表論文】

Nghia Trong Vo, Eiichi Kusagawa, Kaori Nakano, Chihiro Moriwaki, Yasunobu Miyake, Sayaka Haruyama, Sayuri Fukuhara, Nhan Trung Nguyen, Phu Hoang Dang, Mai Thanh Thi Nguyen, Takao Kataoka

Biological evaluation of alkyl triphenylphosphonium ostruthin derivatives as potential anti-inflammatory agents targeting the nuclear factor κB signaling pathway in human lung adenocarcinoma A549 cells

BioChem, 1, 107–121 (2021)