• Class: Hypnotic, anesthesia induction agent.

• Action: GABA effect - Neurotransmitter in the CNS responsible for the regulation muscle tone

• Indications: Induction for rapid sequence intubation (RSI) - anesthesia

• Adverse Effects: Hypotension, respiratory depression, transient skeletal muscle movement, nausea/vomiting, apnea, hiccups, laryngospasm, snoring, cardiac arrhythmias.

• Contraindications: Known sensitivity - pediatric sepsis.

• Special Considerations: Pregnancy Class C

Dosages:

Adults:

• 0.3 mg/kg slow IV/IO push, standard dose 20mg

Pediatrics:

• None