• Class: Anti-hypoglycemic, carbohydrate 

• Action: Increases blood glucose concentrations

• Indications: Documented hypoglycemia 

• Adverse Effects: Hyperglycemia, warmth, burning from IV infusion, tissue necrosis

• Contraindications: Intracranial pressure, hypersensitivity, severe dehydration

• Special Considerations: Pregnancy Class C

Dosages:

Adults:

• 12.5-25g of D50% IV/IO 

• 250 ml of D10 IV/IO

Pediatrics: 

• 0.5-1mg/kg of a 25% solution for >1 year old 

Mixing:

• Newborn up to 3 kg:  administer DEXTROSE 10% 5 mL/kg IV.   Mix by adding 12 mL saline to 3 mL dextrose 50% and then give 5, 10, or 15 mL. 

• Infants/children > 3 kg to 37 kg:  administer DEXTROSE 25% 

2 mL/kg IV.   Mix 25 mL dextrose 50% with 25 mL saline. 

OPTION: Infants/Children >3 kg to 37kg: administer Dextrose 10% 5mL/kg IV.