Introduction
Illustrated mechanism of action
Examples of Medication Brand Names (with Images)
Indication
Side Effects
Precautions & Contraindications
Monographs
Reference
Introduction
Since their introduction over five decades ago, beta-blockers have revolutionized the landscape of cardiovascular medicine.The inception of beta blockers dates back to the 1960s when Sir James Black pioneered the discovery of propranolol, a non-selective beta-adrenergic receptor antagonist. This breakthrough marked a pivotal moment in medical history, the beginning of an era of beta-blockers and laying the foundation for subsequent drug development in this classBeta-blockers are drugs that can lower stress on the heart and blood vessels by blocking the action of adrenaline. They can also help manage migraine, anxiety, tremor, and other conditions.
Illustrated mechanism of action
Medication Brand Names
Propranolol
Metolol (Metoprolol)
Ateno (Atenolol)
Bisoprolol
Carvid (Carvedilol)
Labetalol
Nebivolol
Betacor (Sotalol)
Brevibloc (Esmolol)
Timolol
Nadolol
Visken (Pindolol)
Indication
Beta-blockers are indicated and have FDA approval for the treatment of tachycardia, hypertension, myocardial infarction, congestive heart failure, cardiac arrhythmias, coronary artery disease, hyperthyroidism, essential tremor, aortic dissection, portal hypertension, glaucoma, migraine prophylaxis, and other conditions. They are also used to treat less common conditions such as long QT syndrome and hypertrophic obstructive cardiomyopathy.
Side Effects
Common or mild beta blocker side effects include:
Low blood pressure
Slow heart rate
Fatigue
Dizziness
Nausea
Constipation
Erectile dysfunction
Decreased sex drive
Insomnia
Nightmares or vivid dreams
Weight gain
Rare but serious beta blocker side effects include:
Heart block
Trouble breathing
Masking the effects of low blood glucose (sugar)
Precautions & Contraindications
A - Asthma
B -Block (heart block)
C - COPD
D - Diabetes mellitus (because beta blockers cause hypoglycemia and also mask the effects of hypoglycemia)
E - Electrolyte imbalance (hyperkalemia)
Monographs
Propranolol
Metoprolol
Atenolol
Bisoprolol
Carvedilol
Labetalol
Nebivolol
Sotalol
Esmolol
Timolol
Nadolol
Pindolol
Reference
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