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Introduction
Illustrated mechanism of action
Examples of Medication Brand Names (with Images)
Indication
Side Effects
Precautions & Contraindications
Monographs
Reference
fluoroquinolones
Introduction
Introduction
Ofloxacin is a synthetic broad-spectrum antibiotic belonging to the fluoroquinolone class. It is used to treat a variety of bacterial infections by inhibiting bacterial DNA replication.
Ofloxacin is a synthetic broad-spectrum antibiotic belonging to the fluoroquinolone class. It is used to treat a variety of bacterial infections by inhibiting bacterial DNA replication.
Illustrated Mechanism of Action:
Illustrated Mechanism of Action:
Ofloxacin works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV, which are essential for DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.
Ofloxacin works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV, which are essential for DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.
(You can add a simple illustration of the bacterial DNA being blocked by the drug, if needed.)
(You can add a simple illustration of the bacterial DNA being blocked by the drug, if needed.)
Examples of Medication Brand Names (with Images):
Examples of Medication Brand Names (with Images):
• Tarivid
• Tarivid
• Floxin
• Floxin
• Oflin
• Oflin
• Oflomac
• Oflomac
• Indication:
Ofloxacin is indicated for the treatment of:
• Respiratory tract infections
• Urinary tract infections (UTIs)
• Skin and soft tissue infections
• Sexually transmitted infections like gonorrhea
• Eye and ear infections (in the form of drops)
Side Effects:
Side Effects:
Common side effects:
Common side effects:
• Nausea
• Nausea
• Diarrhea
• Diarrhea
• Headache
• Headache
• Dizzines
• Dizzines
• Insomnia
• Insomnia
Serious side effects (less common):
Serious side effects (less common):
• Tendon rupture
• Tendon rupture
• QT prolongation
• QT prolongation
• Seizures
• Seizures
• Peripheral neuropathy
• Peripheral neuropathy
Precautions & Contraindications:
Precautions:
• Use with caution in patients with seizure disorders
• Avoid excessive sunlight (risk of photosensitivity)
• Monitor liver and kidney function during prolonged use
Contraindications:
• Hypersensitivity to ofloxacin or other quinolones
• Children and adolescents (due to risk of joint/tendon damage)
• Pregnant and breastfeeding women
Monographs
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