Left anterior descending a.

The anterior interventricular (left anterior descending, LAD) branch of the left coronary artery travels inferiorly in anterior interventricular sulcus to the apex of the heart. It supplies the anterolateral myocardium, apex, and and anterior 2/3 of the interventricular septum. The LAD typically supplies 45-55% of the left ventricle (LV).

The anterior interventricular artery provides much of the oxygenated blood to the myocardium of the left ventricle, which in turn provides much of the propulsive force for ejecting oxygenated blood to the systemic circulation via the aorta. Blockage of this artery is particularly associated with mortality.