Welcome to the Starr Lab

Left to right: Quincy Gu, Mihir Shetty, Tim Starr, Chris Clark, Zenas Chang, Wilaiwan DuRose, Christina Landis, Anna Strauss, Conor Nath. Not pictured: Michael Chandler, Jesse Heinen, Angela Nguyen, Pov Thao
Mission Statement 
    In the Starr lab our mission is to understand the genetics of cancer in order to develop individualized, targeted therapies for treating people with cancer
    To bring precision medicine to the cancer clinic we need to understand the underlying genetic causes of cancer. Before we can treat a patient with targeted therapies we need to know what genetic mutations and other genetic events are causing that patient's cancer to grow. In the Starr lab we have developed transgenic mouse models that are capable of identifying the genetic changes that turn a normal cell into a cancerous cell. Using these models we have discovered a large number of genes that likely cause cancer in humans when mutated. We are currently studying the function of these genes in order to determine whether they could be targeted using existing or new drugs. We are also working in close collaboration with bioinformaticists to use the data generated by our mouse models to define the genetic networks that are disrupted during cancer initiation and progression in human tumors. The long-term goal of our research is to develop combinatorial, targeted therapies for treating cancer patients.

    Dr. Tim Starr is an Assistant Professor in the Department of Ob-Gyn & Women's Health, with an adjunct appointment in the Department of Genetics, Cell Biology & Development. He is a member of two graduate programs: Molecular, Cellular, Developmental Biology & Genetics (MCDB&G) and Molecular Biology, Immunology and Cancer Biology (MICaB).  Dr. Starr is also affiliated with the Masonic Cancer Center and the Center for Genome Engineering.