Erste Patienten / China
Wuhan – Eine Untersuchung der Lungenresektate von 2 Lungenkrebspatienten, bei denen später COVID-19 diagnostiziert wurde, liefert im Journal of Thoracic Oncology (2020; doi: 10.1016/j.jtho.2020.02.010) erstmals Einblicke in die frühen histopathologischen Veränderungen bei einer Infektion mit SARS-CoV-2. https://www.aerzteblatt.de/nachrichten/109723/COVID-19-Wie-die-Viren-die-Lunge-fruehzeitig-schaedigen
https://www.thelancet.com/action/showPdf?pii=S0140-6736%2820%2930183-5
The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in Wuhan to determine the epidemiologic characteristics of NCIP. https://www.nejm.org/doi/full/10.1056/NEJMoa2001316
family cluster study:
In this study, we report the epidemiological, clinical, laboratory, radiological, and microbiological findings of five patients in a family clusterwho presented with unexplained pneumonia after returning to Shenzhen, Guangdong province, China, after a visit to Wuhan, and an additional family member who did not travel to Wuhan. Phylogenetic analysis of genetic sequences from these patients were done. https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(20)30154-9.pdf