5M Lifestyle


https://bit.ly/5MLifestyle



(Ida Lupino Cornell Wilde 1942)


5M-lifestyle of

1) Moderate to high intensity levels but melodically or mentally and religiously practiced physical activity as opposed to the weekend gym warrior style fits of exercise marathoning,

2) Mediterranean or DAMP diet, with moderation of alcohol use

3) Mindfulness or mindful meditation or its equivalents like yogic meditation or flow state or a generally mindful and attentive living in the moment type habit.

4) Modulated breathing exercise, or Mindful Belaboured (modulated) Breathing Session is advocated as Vrisch breathing. This insures with high probability both the splendid sleep and stress smashing objectives

5) Monkish mindset-grinvar Meaning or purpose driven life of Altruism Compassion and Empathy (the ACE triad) – a purpose driven life etc.

Meudaimonia. Meaningful existence and matting-mingling offer healthspan benefits.


Inspired by the wisdom of Prof Mark Jackson : Life begins at 40: the demographic and cultural roots of the midlife crisis The Winner of 2019 Wilkins–Bernal–Medawar lecture Published:25 March 2020

https://doi.org/10.1098/rsnr.2020.0008

In 1965, the psychoanalyst and social scientist Elliott Jaques introduced a term, the ‘midlife crisis’, that continues to structure Western understandings and experiences of middle age. Following Jaques's work, the midlife crisis became a popular means of describing how—and why—men and women around the age of 40 became disillusioned with work, disenchanted with relationships and detached from family responsibilities. Post-war sociological and psychological studies of middle age regarded the midlife crisis as a manifestation of either biological or psychological change, as a moment in the life course when—perhaps for the first time—people felt themselves to be declining towards death. Although the midlife crisis has often been dismissed as a myth or satirized in novels and films, the concept has persisted not only in stereotypical depictions of rebellion and infidelity at midlife, but also in research that has sought to explain the particular social, physical and emotional challenges of middle age. In the spirit of the pioneering research of John Wilkins, John Bernal and Peter Medawar, each of whom in different ways emphasized the complex interrelations between science and society, I want to argue that the emergence of the midlife crisis—as concept and experience—during the middle decades of the twentieth century was not coincidental. Rather it was the product of historically specific demographic changes and political aspirations—at least in the Western world—to keep alive the American dream of economic progress and material prosperity.


Mismanaged meta-midlife moribund morbidity mega-neurosis & maladaptive morbidogenic mysterious midlife midgut meloning. This theory supports a key role of mid-life neurosis (crisis) in genesis of morbidogenic mysterious midlife midgut meloning and metabolic syndrome medical mayhem. Relying upon the wisdom of Professor Mark Jackson, winner of the 2018 Wilkins-Bernal-Medawar Medal in his May 2019 lecture at The Royal Society entitled Life begins at 40: the biological and cultural roots of the midlife crisis, which from biological perspective be renamed as death begins at 40. This gives credence to neurobiology theory which heavily engages the mind in morbidity, debilitation and premature death etc. He cites Elliot Jaques from ‘Death and mid-life crisis (1965)’ that “the paradox is that of entering the prime of life, the stage of fulfillment, but at the same time the prime and fulfilment are dated, Death lies beyond” concludes that beyond the 39th birthday the dreadful anticipation of downhill path to death triggers chronic anxiety state with components of depression. Moral of mismanaged meta-midlife moribund morbidity mantra is success with battle of the bulge is a major predictor of longevity past 80. By taking an aging association anxiety it is helpful to view this a hypochondriacal and an ego shattering mindset of feared old age past mid-life tempts the modern men and to a lesser extent woman (esp. if they work outside the home) to deny and resist aging in maladaptive ways. That delusional and pretentious behavior tends to take the characteristics of hypomania through lavish spending, promiscuity, tireless working out etc., which unlike when the same activities are authentically engaged produce joy but fail to do so in both the hypomania or mania of bipolar disorder and the midlife mega-neurosis, aiming to fight the biological clock of age. Success with aging retardation requires engaging in these steps authentically but tend to be done deceptively or unauthentically in deceitful ways and the aging is attempted to be covered up by external approaches like hair coloring, plastic surgery and facial make-up use etc., while ignoring the authentic strategies aimed at hippocampal volume restoration and NESDAC through 5M-lifestyle of 1) moderate to high levels but melodically or mentally and religiously practiced physical activity as opposed to the weekend gym warrior style fits of exercise marathoning, 2) Mediterranean or DAMP diet, 2) mindfulness, 3) modulated breathing exercise, or Mindful Belaboured (modulated) Breathing Session is advocated as Vrisch breathing. 4) moderation of alcohol use 5) monk mindset-grinvar with ACE – a purpose driven life etc. The chronic anxiety state – is rooted in denial of the reality of being hit by the aging process. A key hurdle in rejecting the aging and resort to dishonest short cuts or backdoor approaches to staying young is failure to prepare the body during adolescence and early youth for the midlife megacrisis. One possible explanation why woman tend to escape the midlife megacrisis esp. if they are committed largely to child rearing and don’t work outside the home is that they have a handy explanation of menopause for the major transition of their bodies after the end of procreative period of life. The ready access to a valid and non-guilt triggering basis for their physical decline insulates them against the need to fight aging by maladaptive strategies which is not available to men and the idea of male menopause or andropause is not socially acceptable given the notion of a lifelong male virility and fertility. In many cases this neurosis is an escape from the cumulative stressors of mundane, regimented, high commute, work mandated slavish life devoid of recreational physical activities and sexual depravity etc. all dictated by the government and the corporate universe with the weekends being dictated by the faith institutions leaving no authentic personal leisure time with funds to spare to savor it pleasurably. Some men tend to take refuge in the shifts in their life circumstances on the menopause and libido loss of their wives, an explanation not available to the single, widowed, divorced men etc. Ready access to female sexual images in the advertisements in media or pornography keeps the temptation among men alive for very long. The propensity to resort to maladaptive approaches to youth among both men and women are culturally driven where high premium is placed on physical attractiveness and youthfulness. There is a socially prescribed biorhythm of life or a social lifetable that must be adhered to in order to be socially accepted such that eyebrows get raised if one is single past 40, a couple is choosing to remain childless or a senior who refuses to retire from job etc., which tends to cause stress to the person in question. A major driver of aging therefore is socially prescribed lifetable or life-rhythm, that effectively dictates the time of death which needs to be changed. Even the government, faith institutes, corporate universe make their contribution to this socially mandated lifetable or life-rhythm challenging which is critical to healthspan extension and lifespan.

It is a paradox of life that we do not begin to live until we begin to die. Death begins at thirty, that is, deterioration of the muscle cells sets in. Most old age is premature, and attention to diet and exercise would enable men and women to live a great deal longer than they do to-day. The best part of a woman's life begins at forty. – Mrs. Theodore Parsons 1917.

Remediation of this midlife megacrisis seems possible through adoption of the advice of Walter B. Pitkin in his book Life Begins at Forty (1932) that would tend to generate a richer, more meaningful, happier and more worthy life after overcoming chronic anxiety state and displacing the deceptive approaches to youthfulness with the authentic type of 5M lifestyle style.

The underlying defect or antithesis or 5M lifestyle is not engaging in the pursuit of Horrors of Happiness in a Hurry, as widely attempted through psychopharmaceuticals and illicit pharmacological agents but instead via a medleny mirthful mirth merrymaking (from Russian adjective медленный = slow) an example of which is carefree dancing in the streets in rgoia style.

The hypomanic like behavior of the affected individuals is an attempt to escape or break away from the social and cultural conventions that are suffocating at home and work while the recreational component is almost missing.

Mental health defect or the neurotic element of midlife megacrisis is contained is a self-serving, self-centered self-preservation narcissictic course of action which is in reality maladaptive and contained in this excerpt from Edmund Bergler’s writing “ I want happiness, love, approval, admiration, sex, youth. All this is denied me in this stale marriage to an elderly, sickly, complaining, nagging wife. Let's get rid of her, start life all over again with another woman. Sure, I'll provide for my first wife and my children; sure, I'm sorry that the first marriage didn't work out. But self-defence comes first; I just have to save myself.”


It is a paradox of life that we do not begin to live until we begin to die. Death begins at thirty, that is, deterioration of the muscle cells sets in. Most old age is premature, and attention to diet and exercise would enable men and women to live a great deal longer than they do to-day. The best part of a woman's life begins at forty. – Mrs. Theodore Parsons 1917.

Remediation of this midlife megacrisis seems possible through adoption of the advice of Walter B. Pitkin in his book Life Begins at Forty (1932) that would tend to generate a richer, more meaningful, happier and more worthy life after overcoming chronic anxiety state and displacing the deceptive approaches to youthfulness with the authentic type of 5M lifestyle style.

The underlying defect or antithesis or 5M lifestyle is not engaging in the pursuit of Horrors of Happiness in a Hurry, as widely attempted through psychopharmaceuticals and illicit pharmacological agents but instead via a medleny mirthful mirth merrymaking (from Russian adjective медленный = slow) an example of which is carefree dancing in the streets in rgoia style.



Pleotropogenome. Despite the somewhat misleading name akin to sugar alternatives this is not true genome but behaves like genome in somewhat limited ways. The gonadal endocrine receptor mediate para-genomic or extra-genomic regulation of these three functions 1) cytoskeleton integrity (possibly mediated via protein and mucopolysaccharide synthesis regulation), 2) neurotransmitter output modulation or regulation and 3) energy production related mitochondrial calcium ion transfer regulation that keeps the injurious impact of free radicals under check allowing only their beneficial use to be extracted can be viewed as the fourth element and supplemental to the non-X & Y chromosomal genome, the enterobiomic genome and the epigenome – a distillation extract of life experiences and exposures. This nomenclature would attempt to involve this set of behavior of sex hormone receptors isolated from several brain regions in the antagonistic pleotropic hypothesis the in-built mechanism to work towards ending the life of the adult animal after the end of procreation purpose that creature comes to existence and matures to procreative prowess. Ability to downregulate the signals from pleotropogenome would then support the pliantropy hypothesis that tends to partly negate the antagonistic pleotropic hypothesis by slowing it down and thus regarding aging, causing a SHEAL effect and desired-dreamed after demise delaying. It is very plausible that the current physical exercise mimetics or kinesiomimetic-caloric restriction or restraint mimetic strategies (exercise plus intermittent fasting) under study as anti-aging strategies produce their desirable effects through the pleotropogenome supportable by observation of restoration of procreative power among laboratory rodents exhibit success in interventions that reverse their age. At the gene modulation level exercise and caloric restriction operate almost identically. The biphasic effect of pleotropogenome could be explained by failure of this system to retain the adaptive only mitochondrial calcium ion buffering function with injurious impact of failed mitochondrial calcium ion transfer regulation allowing the free radicals to inflict grave injury to the cells. The way the 5M lifestyle brings out beneficial effect would then be through allowing pleotropogenome to retain its power to keep the mischief of free radicals under check through effective calcium ion buffering capacity. The assumption that this all takes place in the brain would align with the proposed modes of effect of all five of the 5M lifestyle prescripitive interentions and also explain by simple oral ingestion of encapsulated anti-oxidants fails to show benefits. It remains unclear if they even make to the mitochondria or impact the calcium ion flow and buffering in any way.