To get the intro event to Primrose, you'll first need to meet some requirements:
Have already worked as a nurse for Dr. Twig
Are in stage 4+ of the game
Have some extra time after work (nothing else planned for that day)
If you meet the above requirements, when going to visit Dr. Twig after work you'll get a new event where he's talking with another scientist. When he notices you, he will tell you to go with the other scientist to help them with their research.
Primrose will then take you to their lab. When arriving they'll ask you to strip. You can get changed as instructed or try and resist. (If you have the hypnosis fetish active you'll get a scene for that here, which you can still resist out of if you don't want to do this).
If you proceed you'll have your first treatment by them. There will come a time in the event where you'll get a choice to give in or try and resist.
If your collar owner is the company, then you'll need 3 willpower to resist
If your collar owner is anyone else, then you can just tug on your collar to resist
If you are not collared you can still resist
After the first treatment, you'll get changed again and leave their lab and head home.
NOTE: You need to accept the treatment and not resist it if you want to move forward with Primrose's events. If you do resist during this event then you'll have another chance to do his first treatment again.
After meeting Primrose for the first time and going through their first treatment, you can get a random event while taking the elevator up to work in the morning where they hop in the elevator between presentations. Nothing of real note happens during this event but you need to see it to progress with them.
This part will focus on if you accepted their treatment in the intro. If you didn't accept and resisted instead then you'll get an event here where you'll go through their first treatment again, if you get that event then make sure to accept then continue here once you visit them again.
When entering Primrose's lab again after the random elevator meeting they'll take you to their living quarters where they'll ask if you came to chat or help with more research.
[Choosing to chat]
When choosing to talk with them, you'll have several options where you can learn more about them and the research they conduct. When you finish talking you are either able to say you want to help with more of their research, or call it a day and head home.
When choosing to talk about him, you'll get an option to ask to hang out with him. When doing this he'll mention that he has a presentation he needs to make on a new doll suit and asks if you'd help with them demo. Accepting will unlock the chance that when you visit him on any day there's a chance that the event will trigger.
After completing the doll suit demo for the Doctor, you'll unlock a new talking option where you can talk about their research project demos. After talking with them about their project demos you'll have the ability to ask to help them with project codename "Barbie".
[Choosing to help with their research]
When choosing to help them with their research, you'll get a couple options:
If Dr. L'Asservi's anger is high
You'll get a VR punishment event.
During this event you'll be disciplined and put more in line with what the company wants.
If Dr. L'Asservi's anger is low
You'll get the VR trial event
During this event you'll go through a trial for new secretaries for the company, at the end of the event when you get out of the VR, the Doctor will ask you a question about the direction of the simulation you just went through, the first choice will set the path to "cooperative", the second choice will set the path to "discipline".
You'll also have the option to switch to just chatting or leaving their lab for the day.
[Doll suit demo]
When visiting Primrose on any day after discussing hanging out with him (talked about in the previous section). Randomly you'll get an event where he has a presentation for a new doll suit and asks for you assistance. Accepting will have you go through the event, the more obedient you are through the event the more XP you'll get. At the very end of the event you'll receive a new kigurumi mask that's used for VR or AR. You'll also get the ability to talk to them about their project demos. Doing this unlocks the next demo presentation event (see previous section for more info).
[Project "Barbie" demo]
After talking to Primrose about their project demos, you'll get the ability to ask to help them with project "Barbie". Choosing this option will take you directly into the event. This event is more straight forward than the last with no deviations for being more obedient or not.
After completing the first presentation demo and getting the kigurumi VR mask, you'll unlock the ability to do home VR training with it.
NOTE: You also need to have bed bondage installed on your bed
When you have both the kigurumi mask and bed bondage you'll be able to choose to do the home VR training when going to bed. There are two options you can choose from either a relaxation VR simulation or a discipline VR simulation.
NOTE: overuse of either of these simulations will lead to a bad end.
After completing the basic VR demos at Primrose's office, talk to him about his new project.
After an initial demo, you will be given a choice between two different routes: one that focuses on employees cooperating together and one that focuses on employees obeying their managers blindly. Each route is made up of five scenes.
Once the final scene is completed, you can choose to participate in the other path.
Once both paths are completed, the player can choose to freely revisit any of the scenes by talking to Primrose in his lab while he is not Evil.