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Premature (Early) Ejaculation

Prevalence

Estimates of the prevalence of premature (early) ejaculation vary widely depending on the definition utilized.
Internationally, more than 20%-30% of men ages 18-70 years report concern about how rapidly they ejaculate.
With the new definition of premature (early) ejaculation (i.e., ejaculation occurring within approximately 1 minute of vaginal penetration), only 1%-3% of men would be diagnosed with the disorder.
Prevalence of premature (early) ejaculation may increase with age.

Premature (early) ejaculation may be more common in men with anxiety disorders, especially social anxiety disorder (social phobia).

There is a moderate genetic contribution to lifelong premature (early) ejaculation.
Premature (early) ejaculation may be associated with dopamine transporter gene polymorphism or serotonin transporter gene polymorphism.
Thyroid disease, prostatitis, and drug withdrawal are associated with acquired premature (early) ejaculation.
Positron emission tomography measures of regional cerebral blood flow during ejaculation have shown primary activation in the mesocephalic transition zone, including the ventral tegmental area.

A persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within approximately 1 minute following vaginal penetration and before the individual wishes it.

The symptom must have been present for at least 6 months and must be experienced on almost all or all (approximately 75%-100%) occasions of sexual activity (in identified situational contexts or, if generalized, in all contexts).
The symptom causes clinically significant distress in the individual.
The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to the effects of a substance/medication or another medical condition.

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