Antibiotics

Antibiotics 

Amoxicillin, ampercillin, pipercillin, ticarcillin

Bacteria-cidal - beta lactam antibiotics

Cell wall synthesis inhibitor - peptigoglycan protein cell wall 

Wide spectrum antibiotics ( gram positive organism Staph and strep, and gram negative - penetrate outer membrane ) 

GI and urinary tract organism such as E Coli 

Amoxicillin: - better bioavaibility - oral 

Respiratory tract infections 

Strep Pharyngitis

Otitis media 

Sinusitis  

Pneumonia 

Hemophilus influenza 

H pylori 

Morxalla Cattarhasis 

lyme disease - borrelia / tick disease

Prophylaxis 

• dental procedures 

• asplenic patients against encapsulated organism 

Ampicillin - IV 

aspiration pneumonia 

enterococcus - anaerobic organism - UTI and endocarditis 

listeria meningitis 

Amox + Clavulonate =Augmentin 

Extended spectrum of penicillin - Unasyn ( tazobactam and Sulbactam ) 

Pipercillin / tazobactam - Pseudomona - tazocin 

broad spectrum of activity against anaerobes and aerobic 

sepsis

hospital acquired pneumonia / other hospital acquired infections 

Cephasporin - beta lactamase antibiotics 

1st generation 

Cephalexin 

Cefazolin 

PEK organisms ( Proteus, ecoli, klebsiella) 

surgical prophylaxis 

2nd generation

Cefuroxime 

HENS ( hemophilus, neiserria, serratia ) 

3rd generation 

Ceftrixone - HACEK organisms and GI organism eg shigella and salmonella 

IM ceftriaxone for gonorrhoea 

lyme disease 

cefotaxime

1st line prophylaxis for pneumonia, ventilator acquired pneumonia / hospital acquired pneumonia  

cross blood brain barrier : serratia mengingitis 

Ceftazadime - cover pseudomona infection 

hemophilus 

4th generation : wide spectrum

Cefepime - penetrate CNS, cover psuedomonas 

bacterial meningitis 

5th generation : wide spectrum

ceftaroline - MRSA 

big gun antibiotics for systemic infections by aerobic organism including pseudomonas 

carbapenam

imipenam 

meropenam - last resort treatment when other antibiotic fail 

coverage for resistant organisms