STEMIs are sometimes misdiagnosed at acute pericarditis, and the ECG in pericarditis is sometimes concerning for STEMI. Distinction is often difficult. 15-20% of “inappropriate” referrals for PCI were due to pericarditis in one study (Larson, JAMA 2017)
Know the differences & use a stepwise approach looking for STEMI first!
Step 1. Do you see any of the following findings that strongly suggest STEMI?
Reciprocal ST depression in any leads (except aVR & V1)
OR for STEMI = 31
STE in lead III > the STE in lead II
OR for STEMI = 21
Horizontal or convex upward ST-segment morphology
OR for STEMI =6
R-T sign or “checkmark sign”
OR for STEMI = 8
Q-waves that you know are new (be cautious it they are old)
Step 2. After looking for STEMI, you can look for features that suggest pericarditis:
Pronounced PR-segment depression in multiple leads (only reliably seen in viral acute pericarditis, may be transient)
Pericardial friction rub
Spodick sign (may be suggestive of pericarditis if no signs of STEMI found)
When in doubt…do serial ECGs and consider CATH!
Look first for factors that rule IN STEMI before you look at PR segments
ST depression (aside from aVR and V1)
STE III > II
Horizontal or convex upward STE
R-T “checkmark” sign
Only look for PR depression and Spodick sign (T-P downsloping) after trying to rule in STEMI
PR depression and Spodick sign may be helpful, but beware...they are not 100% specific to pericarditis!
References:
Witting MD, Hu KM, Westreich AA, Tewelde S, Farzad A, Mattu A. Evaluation of Spodick’s Sign and Other Electrocardiographic Findings as Indicators of STEMI and Pericarditis. J Emerg Med. 2020;58(4). PMID: 32222321
Larson DM, Menssen KM, Sharkey SW. “False-Positive” Cardiac Catheterization Laboratory Activation Among Patients with Suspected ST-Segment Elevation Myocardial Infarction. JAMA. 2007;298(23):2754-2760. PMID: 18165668
Chhabra L. Loss of a cardiology legend: A tribute to Professor David H. Spodick (1927-2019). J Electrocardiol. 2019 Sep-Oct;56:125-127. PMID: 31277841
Related Topics:
STEMI vs. LV Aneurysm