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Normalization of previously abnormal T waves. A phenomenon of reocclusion of an artery that had recently achieved reperfusion. T waves become inverted with reperfusion, and reocclusion is thought to cause the T wave to become hyperacute or upright again!
First described in the 1970s
At rest or during exercise testing, suggestive of reversible ischemia or coronary occlusion
May be an early or only marker of ischemia
KEY PEARL:
Pseudonormalization is a concerning finding for reocclusion in patients with ACS. When getting serial ECGs, always look for evidence of hyperacute T waves or new upright T waves in leads where they were recently inverted (pseudonormalized T waves)
Pretty cool huh? Now learn more about T waves here!
Reference:
Simons A, Robins LJ, Hooghoudt TE, Meursing BT, Oude Ophuis AJ. Pseudonormalisation of the T wave: old wine?: A fresh look at a 25-year-old observation. Neth Heart J. 2007;15(7-8):257-259. PMID:17925836
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