Watch out for this T-wave abnormality that is high risk for extensive anterior wall MI and death!
2 types of Wellens' waves
Type 1 - Deeply symmetric TWI
Type 2 - Biphasic T waves with terminal TWI. Goes up first, then down (often misdiagnosed as “normal” or “non-specific T-wave abnormality”).Pattern of T-wave abnormality in mid precordial leads (V2-V3, +/-V4)
Highly specific for critical obstruction of the proximal LAD
High risk for extensive anterior wall MI and death
ST changes are often absent and patient can be chest pain free!
Cardiac biomarkers often initially normal
Best to diagnose in absence of high voltage, as there are normal variants, see "pseudo-wellens"
When in doubt get serial ECG’s, some will evolve into STEMI!
Reference:
Wang K, Asinger RW, Marriott HJL. ST-segment elevation in conditions other than acute myocardial infarction. N Engl J Med 2003;349(22):2128–35. PMID: 14645641