Top causes of widening of the QRS complex to consider:
Bundle branch blocks (LBBB or RBBB) & Paced beats/rhythms
Na+ channel blocking drugs/medications (e.g. TCA’s)
Pre-excitation syndromes (e.g. WPW)
Metabolic (e.g. hyperkalemia or severe acidosis)
Non-specific intraventricular conduction delay (e.g. LVH, cardiomyopathy)