List of Poisons/Drugs

Acetone (Light) (5 uses); Can't do verbal spells

Amaryllis (Medium) (4 uses); -1 DEX, -1 CON

Amnesic Shellfish Poisoning (Extreme) (2 uses); Confusion spell effects, DC 15 concentration, short-term memory lost, then coma/death

Amphetamines (High) (3 uses); Disadvantage on perception rolls and attack rolls

Antihistamines (Light) (5 uses); Disadvantage on perception rolls/attack rolls, confusion spell effects

Arsenic (High) (3 uses); -2 STR, -2 CON, hard time eating stuff

Aspirin (Medium) (4 uses); Disadvantage on perception/attack rolls, then Coma

Bath Salts (Vicious) (1 use); Confusion, Hallucinations, -4 STR, DC 15 concentration, then death

Benzocaine (Medium) (4 uses); Loses 6d4 hp for 1d6 rounds, DC 15 concentration

Benzodiazepines (Extreme) (2 uses); Can't use verbal spells, confusion spell effects, seizing

Black Widow (Extreme) (2 uses); -3 DEX, -3 CON, -3 STR, -10ft

Brown Recluse (High) (3 uses); -2 STR, -2 DEX, DC 15 concentration

Buprenorphine (Negligible) (6 uses); DC 15 concentration, memory lost

Cigarettes (High) (3 uses); Confusion spell effects, -2 STR, DC 15 concentration

Cimetidine (High) (3 uses); Confusion spell effects, disadvantage on attack rolls, DC 15 concentration

DEET (High) (3 uses); -10ft, seizures, then coma

Dextromethorphan (Vicious) (1 use); Loss of consciousness, brain dead or death

Ethanol (Extreme) (2 uses)

Ethylene Glycol (Extreme) (2 uses)

False Hellebore (Extreme) (2 uses); Coma

Famotidine (High) (3 uses) 

Fentanyl (Vicious) (1 use); Death

Fluoride (Medium) (4 uses)

Graphite (Light) (5 uses)

Guaifenesin (Medium) (4 uses)

Guanfacine (Medium) (4 uses); Disadvantage on attack rolls

H2 Blockers (High) (3 uses) Confusion spell effects, unable to use verbal spells

Heroin (Extreme) (2 uses) Loss of Consciousness, -3 STR, -10ft

Ibuprofen (Light) (5 uses); Blurred vision, Can't speak

Indian Pokeweed (High) (3 uses); -2 STR, then loss of consciousness

Inhalants (High) (3 uses); -2 DEX, Hallucinations, then Brain damage

Ipecac (Medium) (4 uses); Confusion

Jerusalem Cherry (Extreme) (2 uses); Confusion, Hallucinations, then Paralysis

K2 (High) (3 uses); Confusion, Hallucinations, Suicidal thoughts

Kratom (High) (3 uses); Frightened, -2 CON

LSD (Extreme) (1 uses); Disadvantage on attack rolls, -3 DEX, -3 STR

Lead (High) (3 uses); -2 DEX, -2 CON, loss of sex drive

Loratadine (High) (3 uses); Disadvantage on attack rolls, -2 STR, can't do verbal spells

Marijuana (Extreme) (2 uses); Disadvantage on attack rolls, -3 DEX

Melatonin (Negligible) (6 uses); Can be surprised, -1 to WIS rolls

Mercury (High) (3 uses); Memory loss, blindness, -2 DEX

Methamphetamine (High) (3 uses); -2 CON, Fear

Methylenedioxymethamphetamine (Extreme) (1 usage); Disadvantage on attack rolls, Hallucinations, -3 CON, -3 DEX

Nicotine (High) (3 uses); -2 DEX, -2 STR, Paralysis

Paralytic Shellfish Poisoning (Vicious) (1 use); -4 STR, -4 DEX, Paralysis, then Death

Poinsettia (Medium) (4 uses); Decrease Concentration, -2 to rolls

Poison Ivy (Negligible) (6 uses); Decrease Concertration

Pseudoephedrine (Medium) (4 uses); -1 STR, Hallucinations 

Radon (Extreme) (2 uses); -10ft, -3 CON, -3 STR, 15 DC concentration

Rhubarb (Vicious) (1 use); Can't use verbal spells, -4 STR, then Coma

Salmonella (Extreme) (2 uses); DC 15 concentration, -3 WIS, disadvatage on attack rolls

Senokot (High) (3 uses); -10ft, uncontrolled diarrhea and vomiting

Sodium Hypochlorite (Vicious) (1 uses); Disadvantage on attack rolls, Confusion spell effects, -4 STR, Can't do verbal spells, then Coma

Suboxone (Negligible) (6 uses); -5ft, Hallucinations

Tagamet

Tenex

THC (Tetrahydrocannabinol)

Timber Rattlesnake

Vaseline

Veratrum Viride

Winter Cherry

Xylenes