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IVDD Screening Special Offer - August 2017 - Just £100 for 9 dogs only

posted 7 Aug 2017, 07:57 by Ian Seath   [ updated 7 Aug 2017, 07:57 ]

Thanks to the generosity of the Little Legs Fundraising campaign we are able to offer further subsidies for dogs screened in August and September. 

Lisa Roylance and Carley Denton have raised £900 and we can therefore offer 9 dogs the chance to be screened for just £100. The normal price is £300 at a CVS referral practice, reduced to £200 with a subsidy from the Breed Council.

Now, on a first come, first served basis, we can offer a further £100 subsidy. You will have to pay the CVS vet £300 and then reclaim £200 from the Breed Council's IVDD Fund.

If you plan to breed from your Dachshund and he/she is aged 24-48 months, you can screen your dog. Contact Ian Seath to apply for the special £200 subsidy. 

A HUGE THANK YOU to everyone who is supporting Little Legs Fundraising.

Safe and Unsafe Mini Wire Lafora Litters - Summer 2017

posted 7 Aug 2017, 03:06 by Ian Seath   [ updated 7 Aug 2017, 03:07 ]

Mandy Dance has kindly analysed the Breed Records Supplement for Summer 2017 and here are the figures for Mini Wire litters:

53 litters producing 199 puppies, of which 4 litters were unsafe (parents untested or carrier to untested), producing 14 puppies at risk of Lafora.



Of the remaining litters, 23 have both parents clear of Lafora and cord1 PRA. 26 litters have one parent who is untested or a carrier.

The trend is for untested bitches to go to clear dogs. It is essential that stud dog owners check the status of these "pet" Bitches coming to their dogs and we strongly recommend that breeders get their bitches tested.

The next screening session is 13th September - contact susan.holt@talktalk.net to book a place.

Lafora Disease - Progression Survey paper published

posted 3 Aug 2017, 02:38 by Ian Seath

Abstract

Lafora disease (LD) is an autosomal recessive late onset, progressive myoclonic epilepsy with a high prevalence in the miniature Wirehaired Dachshund. The disease is due to a mutation in the Epm2b gene which results in intracellular accumulation of abnormal glycogen (Lafora bodies). Recent breed-wide testing suggests that the carrier plus affected rate may be as high as 20%. A characteristic feature of the disease is spontaneous and reflex myoclonus; however clinical signs and disease progression are not well described. A survey was submitted to owners of MWHD which were homozygous for Epm2b mutation (breed club testing program) or had late onset reflex myoclonus and clinical diagnosis of LD. There were 27 dogs (11 male; 16 female) for analysis after young mutation-positive dogs that had yet to develop disease were excluded. Average age of onset of clinical signs was 6.94 years (3.5–12). The most common initial presenting sign was reflex and spontaneous myoclonus (77.8%). Other presenting signs included hypnic myoclonus (51.9%) and generalized seizures (40.7%). Less common presenting signs include focal seizures, “jaw smacking”, “fly catching”, “panic attacks”, impaired vision, aggression and urinary incontinence. All these clinical signs may appear, and then increase in frequency and intensity over time. The myoclonus in particular becomes more severe and more refractory to treatment. Signs that developed later in the disease include dementia (51.9%), blindness (48.1%), aggression to people (25.9%) and dogs (33.3%), deafness (29.6%) and fecal (29.6%) and urinary (37.0%) incontinence as a result of loss of house training (disinhibited type behavior). Further prospective study is needed to further characterize the canine disease and to allow more specific therapeutic strategies and to tailor therapy as the disease progresses.


Download the Open Access paper here.

Lafora Screening Session - September 13th 2017

posted 17 Jul 2017, 09:41 by Ian Seath   [ updated 17 Jul 2017, 10:48 ]

https://sites.google.com/site/ukdachshundhealthreport/dachshund-health-resources/lafora-disease
The Wirehaired Dachshund Club's Lafora Sub-committee has confirmed the date for the next Screening Session to be September 13th 10 am to 1 pm at Poole House Vets, Lichfield.

To book a place, please contact Sue Holt or Nora Price.

The WHDC is pleased to be able to offer these tests at a subsidised cost of £150 per dog (for UK owners).

Read more about Lafora Disease in Miniature Wirehaired Dachshunds.

To Boost or not to Boost? Davies Veterinary Specialists Webinar

posted 6 Jul 2017, 02:34 by Ian Seath   [ updated 6 Jul 2017, 02:34 ]


To Boost or not to Boost? An insightful webinar regarding ‘Vaccination Dilemmas’- presented by Nat Whitley, RCVS & European Specialist in Small Animal Medicine and Head of Internal Medicine at Davies. 

Managing Fading Puppies - webinar 2/8/17

posted 1 Jul 2017, 10:17 by Ian Seath

Managing Fading Puppies; Practical advice at a critical time; with Gary England

The email address you're registering with is already in use. Please register using an alternate email address.


This webinar meets 1 times.

Wed, Aug 2, 2017 6:00 PM - 7:00 PM BST

Effective puppy management is an essential ingredient to successful breeding. In this webinar, Gary England, Professor of Comparative Veterinary Reproduction at the University of Nottingham will discuss what pro-active changes we can make if faced with a ‘fading’ puppy. 

Lafora Litters test status - Spring 2017

posted 21 May 2017, 09:34 by Ian Seath   [ updated 21 May 2017, 09:35 ]

Thanks, once again, to Mandy Dance for updating our analysis of safe and unsafe Lafora litters from the Spring 2017 KC Breed Records Supplement.



This quarter, there were 53 safe and 3 unsafe litters. A "safe" litter is where there is no risk of Lafora-affected puppies being born.
This quarter:

  • 56 litters producing 214 puppies.
  • 27 litters with both parents clear for Lafora AND cord1 PRA.
  • 14 litters where the sire is clear for Lafora and the dam is either a carrier or untested.
  • 2 litters producing 5 puppies where neither parent was tested.
  • 1 litter where both parents are known carriers producing 4 puppies

Dachshund Breed Council Improvement Strategy - 2017

posted 22 Apr 2017, 14:32 by Ian Seath   [ updated 22 Apr 2017, 14:33 ]

Ian Seath's presentation at the IPFD International Dog Health Workshop 2017 on the UK Dachshund Breed Council's Health Improvement Strategy.

UK IVDD Screening programme

posted 10 Apr 2017, 02:38 by Ian Seath   [ updated 13 Apr 2017, 09:28 ]

For the avoidance of doubt, the UK IVDD Screening programme is just that: a SCREENING PROGRAMME. You could also call it a TEST (like Hip or Elbow testing). 

There is also a research component in that we are tracking the dogs that have been screened. It is NOT "research" to see if it might work. 

It is based on decades of research (starting in the 1960s) that shows a relationship between calcifications and IVDD. The lower the number of calcifications, the lower the risk of IVDD.  It is about reducing the RISK of herniations in future generations. As with the hip and elbow schemes which don't guarantee freedom from these issues, it does not guarantee avoidance of herniation.

Please read the information here: Why x-ray screening?


Mini Wire Lafora Litter status - Winter 2016

posted 10 Feb 2017, 12:10 by Ian Seath   [ updated 10 Feb 2017, 12:11 ]

We are grateful to Mandy Dance for collating the latest KC Breed Records Supplement data on Lafora status of litters registered in the last Quarter of 2016.

There were 30 litters recorded producing 105 pups, however, one litter was an odd registration as it had no known sire (!) and so we have discounted this. Therefore the figures are based on 29 litters and 104 pups.
  • Completely safe 14 litters producing 45 pups
  • Completely unsafe 3 litters producing 12 pups
The remaining litters will be safe due to the Breeder using a clear stud dog, however, none of these dams have been tested.

Overall the trend remains the same percentage-wise regarding Lafora, with around 90% of litters being safe.


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