SDCA Journal of Biological Research

Abstract

The leaf extract of Tamarindus indica (Tamarind) was investigated for antimicrobial activity at different concentrations via disc diffusion method and spot test against Extended Spectrum Beta-Lactamase Escherichia coli and Methicillin Resistant Staphylococcus aureus. The antimicrobial activity of the different concentrations (100mg/ml, 75mg/ml, 50mg/ml, 25mg/ml) of the leaf extract was compared to the positive and negative control groups. Based on the results obtained and interpreted from the experimentation, the study concludes that T. indica leaf extract with the concentrations of 100mg/ml, 75mg/ml, and 50mg/ml has antimicrobial activity against Methicillin Resistant S. aureus via spot test and there is significant difference (p<0.05) between the three concentrations, thus having different antibacterial activity. The average diameter of the zone of inhibition exhibited by 100mg/ml of the extract was 13.33mm, 11.67mm for the 75mg/ml, and 10.33mm for the 50mg/ml concentration.

Keywords: Tamarindus indica, antibacterial, medicinal plant, multidrug resistant bacteria.