Please see below the list of studies available in the region for Primary Care sites. Should you be interested in any of the studies, please do not hesitate to send us your Expression of Interest and one of our colleagues will contact you to discuss further.
Primary Care
Identifying the Prevalence of Social Isolation and Loneliness in the Community Setting Across England
This study aims to measure the extent that individuals are feeling lonely and/or socially isolated using a brief eSurvey including validated questions (UCLA-3-item loneliness scale & ONS Direct measure of loneliness). Data collected will be used to create a 'heat map' of loneliness at local authority, city & regional levels to drive evidence-based commissioning decisions.
Primary Care
The Discover Me study aims to collect health and genetic data from consenting study participants to create a dynamic research resource.
The Discover Me study aims to collect health and genetic data from consenting study participants to create a dynamic research resource. The resource will facilitate research to help us better understand genetic risk of disease susceptibility and severity, as well as insights into drug response and adverse events in the primary care setting. This will provide a research framework to integrate genetic information into primary care in the future.
Stroke
The SAFER Trial: Screening for Atrial Fibrillation with ECG to Reduce stroke - a randomised controlled trial
Atrial fibrillation (AF) is a heart condition that causes irregular heartbeat. It affects up to 1 in 10 people over the age of 65. AF greatly increases risk of stroke, but treatment with blood thinning (“anticoagulant”) medication can stop this happening. About 10% of strokes happen in people unaware they have AF. Detecting AF can be difficult because it often comes and goes, and may not cause symptoms.
Many clinicians think the NHS should promote AF screening. The UK National Screening Committee has highlighted a lack of evidence that detecting AF in people by screening would benefit them.
We are therefore undertaking a large 8-year programme of work to find out if screening for AF in people aged 65 and over does prevent stroke and other problems like heart attacks, does not cause significant harm, and represents good value-for-money for the NHS. The SAFER Trial is a cluster randomised trial that will address these questions.
Dementia
‘Active Brains’ website to help older adults to look after their brain and body health
The aim is to help prevent problems with things like remembering, concentrating or reasoning (known as cognitive decline). The website will help older adults to make simple changes such as getting more active, playing brain training games and finding ways to eat more healthily. This research will test how well the website works.
How general practice team composition and climate relate to quality, effectiveness and human resource costs
General practice is under pressure due to increasing workload and a shortage of GPs and other primary care staff. New forms of practice are also emerging. Our aim is to explore how the composition of GP teams, and the relationships among team members (called team climate) affects the quality of care and health outcomes for patients, and the costs for the practice.
Respiratory
Quality-of-life in patients with long COVID: harnessing the scale of big data to quantify the health and economic costs
OpenPROMPT aims to understand the impact of long COVID on quality-of-life in adults in English primary care.
One way of assessing the impact of long COVID is to measure quality-of-life through a standard questionnaire, which can then be used to understand the costs of long COVID to the NHS and wider economy.
The impact of long COVID on these measures is not currently known. It is important to understand who is worst affected by long COVID and the cost to the NHS, so that strategies like booster vaccines can be prioritised to the right people.
Primary Care
Evaluation of aid to diagnosis for developmental dysplasia of the hip (DDH) in general practice
The primary aim of the trial is to improve the diagnosis of DDH in primary care by:
a) reducing the number of ‘clinically insignificant’ referrals to secondary care and
b) reducing the number of infants with a missed or late diagnosis of DDH