SPIROMAC (CPMS 53202, IRAS 306946)

UPDATED - 14/02/2023

SPIROmetry to Manage Asthma in Children (SPIROMAC)

The aim of the study is to compare treatment guided by spirometry plus symptoms (intervention) against treatment guided by symptoms alone (standard care), in children with asthma who are at risk of an asthma attack. All participants, carers and usual clinical teams will be blinded to allocated treatment (randomised arms). 550 children aged 6-15 years will be recruited. The study website incorporates a treatment algorithm that will be run at the end of the baseline visit and at each of the follow-up visits (3, 6, 9, 12 months) to advise on the preventive treatment for the following 3 months (no change, a reduction, or an increase in preventive treatment or that the opinion of a member of the clinical team be sought).

Inclusion & Exclusion Criteria

Inclusion criteria, potentially eligible to be invited to take part:

1. Aged 6-15 years

2. Asthma diagnosis confirmed by a doctor or a respiratory/asthma specialist nurse (or Read code for asthma if recruited in primary care)

3. Patient/parent reported-asthma attack treated with at least one course of oral corticosteroids in the 12 months prior to recruitment 

4. Be able to perform spirometry

5. Be able to understand written/spoken English.

Exclusion criteria, not to be invited to take part: 

1. Not being able to perform spirometry satisfactorily 

2. Presence of another chronic respiratory condition (e.g. cystic fibrosis)

3. Current treatment with maintenance oral steroids and biologicals (we cannot provide standardised step up/down treatment options).

Study Resources

Access for the SystmOne and EMIS study resources can be requested below.

For further guidance on using the resources, please refer to the guidance documents and further useful information on the PRIDES page.

If you have any questions about using the resources provided or would like to be involved in the development of future resources please get in touch through the Contact Page.

Disclaimer:

Please note the resources provided are designed to assist with the identification of potentially suitable patients and to appropriately code these patients if required.

These resources have been developed based on the criteria provided by the relevant study team and whilst every effort has been made to make them universally implementable they rely on read codes and the data stored in the individual practice's clinical system. These resources are intended to assist with identification but should be used in conjunction with clinical oversight and a clear understanding of the study parameters.

While we endeavour to keep the information, tools and resources provided up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the tools provided for any purpose. Any reliance you place on such information is therefore strictly at your own risk.

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