Clinical Use & Dose

 Clinical use

• can be effective in the treatment of atrial, junctional, and ventricular arrhythmias. 

• The standard intravenous dose is 100 mg every two minutes, repeating this to a total of 1000 mg over the first hour. 

• Oral treatment may be given as prophylactic therapy.

Dose

Intravenous (IV) Dose:

• Initial IV doses typically range from 1 mg/kg to 2 mg/kg of body weight.

• These initial doses are often administered over a period of 5 to 10 minutes.

• Intravenous infusions may follow the initial bolus dose, with infusion rates ranging from 0.5 mg/kg/hour to 2 mg/kg/hour, depending on the drug.

Oral Dose:

• Initial oral doses can vary widely, usually starting from 100 mg to 400 mg, depending on the specific drug and patient factors.

• Oral doses are typically administered every 6 to 12 hours, with some drugs requiring more frequent dosing.

• Doses may be adjusted based on individual patient response and tolerability, with gradual titration as needed.

• It's important to note that these dosing ranges are general guidelines, and specific dosing recommendations should be based on the individual patient's clinical condition, renal and hepatic function, concomitant medications, and other relevant factors.

• Always refer to the drug's prescribing information and consult with a healthcare professional for precise dosing instructions.