BBCCT-105

Proteins (Theory)

About the Course

Dear learners welcome to the second semester of your BSc honours in Biochemistry. We hope you have enjoyed learning the basic concepts of biomolecules and cell biology in your previous semester. In this semester you will be studying two core courses of Biochemistry that includes proteins and enzymes.

However, the first course that is proteins will be dealt in detail in this volume of BBCCT- 105. Since you have studied about amino acids and their interactions leading to the formation of protein structures in the first semester (BBCCT-101). Hence in this course you will be studying in detail about the higher order of protein structure, bio analytical techniques that are are used widely for the purpose of extraction isolation and separation arf proteins. Apart from these topics, this course is designed to explain certain special functions of proteins like structural components and immune molecules. This course will also discuss about the basic concepts on folding of proteins.

Self Learning Material

Block-1.pdf

The Block 1 of this course titled as "Proteins: isolation and separation". This block consists of of 4 units discussing the various interactions among amino acids, that are essential for the maintenance of protein structure as well as the diverse functions exhibited by proteins. Along with this you will also study about extraction of proteins using different biophysical methods. The last two units of this block will discuss about separation techniques ranging from simple fractionation to advanced chromatographic techniques.

Block-2.pdf

Block 2 of this course deals with "characterization and analysis of proteins". This block consists of 3 units where the first unit is dedicated to the characterization of proteins using electrophoresis. The second unit of this block explains about sequencing and analysis of proteins using enzymatic and chemical methods.

Block-3.pdf

The 3rd block of this course will be explaining about structural aspects of proteins. The first unit of this block describes about three-dimensional structure of proteins where you will be learning about bond length, different configurations. Ramachandran plot which is significant in understanding the secondary structure of a protein has been discussed in detail. The third unit of this block explain about protein folding. Last unit of this block which is significant with respect to research in the field of proteins using computer-based skills is "protein structure databases".

Block-4.pdf

The block 4 is the last block of this course which describes the diversity of protein function. First unit narrates about proteins as transport, storage, receptor and signalling molecules. The second unit discusses in detail about the two important proteins like myoglobin and hemoglobin. The last unit is dedicated to specialised proteins in which you will be studying about antibodies and actin myosin filaments.

Video Resources

If you have any query about this course, please feel free to Contact:

Dr. M. Abdul Kareem

Course Coordinator, Proteins (BBCCT-105 & BBCCL-106)

Assistant Professor in Biochemistry

Block-D, School of Sciences, Biochemistry Discipline

Email: abdul.kareem@ignou.ac.in