A. cleaning the acute probes:
Based on a NeuroNexus document released on 2012 (attached file in this page), we can clean the probes after acute recordings as follows:
1. For A-Probes/packages: After withdrawal from tissue after an experiment, immediately rinse with a gentle stream of distilled water. Soak the probe (only the silicon shank;
avoid soaking the silicone coating) in a protein-dissolving detergent or enzyme such as contact lens solution or diluted surgical instrument detergent. This process may take a
few hours.
2. NeuroNexus recommends cleaning with an alcohol rinse after in vitro preparation. After in vivo use, isopropyl alcohol (e.g. 70% IPA) can be used for cleaning AFTER the protein dissolving procedure (See Step 1).
CAUTION: Without first dissolving the residual tissue from the probe, alcohol could cause protein to stick to the electrode sites.