SKC Science & Technology Webinar

Bottom-up engineering: from protein molecules to stem and immune cells


Date/Time: Saturday, March 5, 2022, 6:00pm Indian Standard Time

Speaker: Rubul Mout, Harvard University and Boston Children's Hospital, USA


Recording at YouTube: https://youtu.be/QR55MjcsKx4


Abstract: Nature has built molecules and assembled them to make larger entities called cells, or life, an incredible phenomenon that happened in the last couple of billions of years. I and my co-workers tried to emulate nature’s intricate process of building protein machines—the machines that power up life. In the past couple of years, we have built large protein assemblies, proteins that never existed in nature before, from scratch. With those protein molecules, we are exploring a vast world of possibilities in further engineering life--from stem cells to immune cells--to fight off diseases.​


Bio: Rubul Mout is a Fellow (Research) at Harvard Medical School, Harvard University, and at the Stem Cell Program, Boston Children’s Hospital (BCH), Boston, USA. Prior to joining Harvard/BCH, he was a Washington Research Foundation Innovation Fellow at the Institute for Protein Design, University of Washington. He received his Ph.D. from University of Massachusetts, Amherst, USA. He is the co-author of more than 35 research articles and the inventor of numerous technologies in gene editing and protein design. Between the years 2014-2018, he developed a technology for intracellular protein delivery and gene editing in mammalian cells, termed as the ‘E-tag’ method, which was published in a series of five research papers. In 2020, he was granted a patent for this technology by USPTO (the United States Patent and Trademark Office). He the author of two books—a collection of short stories and a memoir—in his native language Assamese.


Target Audience: This is for a wider audience. In particular, higher secondary and college students and teachers are welcome.

This webinar will be conducted over Zoom. The Zoom link will be available to registrants (sent to their email addresses) shortly before the webinar starts.

This webinar is part of SKC Science and Technology Webinar Series.

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