How is gene expression changed in a cell?
How can patterns of gene expression be conserved through inheritance?
What mechanisms are there for inhibition in biological systems?
In what ways does the environment stimulate diversification?
D2.2.1 AHL Gene expression as the mechanism by which information in genes has effects on the phenotype
D2.2.2 AHL Regulation of transcription by proteins that bind to specific base sequences in DNA
D2.2.3 AHL Control of the degradation of mRNA as a means of regulating translation
D2.2.4 AHL Epigenesis as the development of patterns of differentiation in the cells of a multicellular organism
D2.2.5 AHL Differences between the genome, transcriptome and proteome of individual cells
D2.2.6 AHL Methylation of the promoter and histones in nucleosomes as examples of epigenetic tags
D2.2.7 AHL Epigenetic inheritance through heritable changes to gene expression
D2.2.8 AHL Examples of environmental effects on gene expression in cells and organisms
D2.2.9 AHL Consequences of removal of most but not all epigenetic tags from the ovum and sperm
D2.2.10 AHL Monozygotic twin studies
D2.2.11 AHL External factors impacting the pattern of gene expression
The power point presentation and the accompanying student notes are used as resources in class - together with activites, discussion, simulations and experiments.