Syllabus statements

D1.2.1 Transcription as the synthesis of RNA using a DNA template

D1.2.2 Role of hydrogen bonding and complementary base pairing in transcription

D1.2.3 Stability of DNA templates

D1.2.4 Transcription as a process required for the expression of genes

D1.2.5 Translation as the synthesis of polypeptides from mRNA

D1.2.6 Roles of mRNA, ribosomes and tRNA in translation

D1.2.7 Complementary base pairing between tRNA and mRNA

D1.2.8 Features of the genetic code

D1.2.9 Using the genetic code expressed as a table of mRNA codons

D1.2.10 Stepwise movement of the ribosome along mRNA and linkage of amino acids by peptide bonding to the growing polypeptide chain

D1.2.11 Mutations that change protein structure

-------------------------------------------------------------------------------------------------------------------------------------------------------------

D1.2.12 AHL Directionality of transcription and translation

D1.2.13 AHL Initiation of transcription at the promoter

D1.2.14 AHL Non-coding sequences in DNA do not code for polypeptides

D1.2.15 AHL Post-transcriptional modification in eukaryotic cells

D1.2.16 AHL Alternative splicing of exons to produce variants of a protein from a single gene

D1.2.17 AHL Initiation of translation

D1.2.18 AHL Modification of polypeptides into their functional state

D1.2.19 AHL Recycling of amino acids by proteasomes