Embedded Files
Guiding questions
Guiding questions
• How does the structure of nucleic acids allow hereditary information to be stored?
• How does the structure of DNA facilitate accurate replication?
Linking questions
Linking questions
• What makes RNA more likely to have been the first genetic material, rather than DNA?
• How can polymerization result in emergent properties?
Syllabus statements
Syllabus statements
A.1.2.1 DNA as the genetic material of all living organisms
A.1.2.2 Components of a nucleotide
A.1.2.3 Sugar–phosphate bonding and the sugar–phosphate “backbone” of DNA and RNA
A.1.2.4 Bases in each nucleic acid that form the basis of a code
A.1.2.5 RNA as a polymer formed by condensation of nucleotide monomers
A.1.2.6 DNA as a double helix made of two antiparallel strands of nucleotides with two strands linked by hydrogen bonding between complementary base pairs
A.1.2.7 Differences between DNA and RNA
A.1.2.8 Role of complementary base pairing in allowing genetic information to be replicated and expressed
A.1.2.9 Diversity of possible DNA base sequences and the limitless capacity of DNA for storing information
A.1.2.10 Conservation of the genetic code across all life forms as evidence of universal common ancestry
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A.1.2.11 AHL Directionality of RNA and DNA
A.1.2.12 AHL Purine-to-pyrimidine bonding as a component of DNA helix stability
A.1.2.13 AHL Structure of a nucleosome
A.1.2.14 AHL Evidence from the Hershey–Chase experiment for DNA as the genetic material
A.1.2.15 AHL Chargaff’s data on the relative amounts of pyrimidine and purine bases across diverse life forms
Resources used in class
Resources used in class
The power point presentation and the accompanying student notes are used as resources in class - together with activities, discussion, simulations and experiments.
1. A 1.2 SL Nucleic Acids - student notes.pdf1. A 1.2 HL Nucleic Acids - student notes.pdfPractice Questions
Practice Questions
Test your knowledge and understanding by going over these past exam questions:
Practice Questions - Nucleic Acids SLHL.pdfPractice Questions - Nucleic Acids - SLHL MS.pdfExtracting DNA from fruits or vegetable is an enjoyable activity to visualize the invisible!
1. PRACTICAL - DNA fruit extraction.pdfDo you want to build your own DNA double helix? Use this DNA Origami to decorate your parent's living room!
1. ACTIVITY - DNAorigami.pdfThe cut and fold activity above is accompanied by a wonderfully relaxing and instructional video, which will take you through all the steps of the DNA origami activity. Highly recommended for those who find craftwork difficult.
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