Syllabus statements

D1.3.1 Gene mutations as structural changes to genes at the molecular level

D1.3.2  Consequences of base substitutions

D1.3.3 Consequences of insertions and deletions

D1.3.4 Causes of gene mutation

D1.3.5 Randomness in mutation

D1.3.6 Consequences of mutation in germ cells and somatic cells

D1.3.7 Mutation as a source of genetic variation

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D1.3.8 AHL Gene knockout as a technique for investigating the function of a gene by changing it to make it inoperative

D1.3.9 AHL Use of the CRISPR sequences and the enzyme Cas9 in gene editing

D1.3.10 AHL Hypotheses to account for conserved or highly conserved sequences in genes