Vagus Nerve Stimulation

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Vagus Nerve Stimulation and Acid Reflux Relief

Vagus nerve stimulation (VNS) is emerging as a potential treatment for acid reflux, particularly in cases where traditional medications aren't fully effective. The vagus nerve plays a key role in regulating the digestive system, including the esophagus and stomach. By modulating its activity, VNS may help improve the function of the lower esophageal sphincter (LES), the muscle that prevents stomach acid from backing up into the esophagus.

Research suggests that stimulating the vagus nerve can enhance gastrointestinal motility and reduce inflammation, both of which are beneficial for controlling reflux symptoms. Non-invasive VNS devices, which deliver gentle electrical pulses through the skin, are currently being explored as a promising, low-risk option.

While more studies are needed to confirm long-term benefits, vagus nerve stimulation offers a novel, holistic approach to managing acid reflux—one that targets the condition's neurological roots rather than just its symptoms.

This paper published in Alimentary Pharmacology and Therapeutics in August 2020, Transcutaneous vagus nerve stimulation prevents the development of, and reverses, established oesophageal pain hypersensitivity, concludes "t-VNS prevents the development of, and reverses established, acid-induced oesophageal hypersensitivity. These results have therapeutic implications for the management of visceral pain hypersensitivity."

This paper published in Frontiers in Neuroscicne March 2024, Integrative effects of transcutaneous auricular vagus nerve stimulation on esophageal motility and pharyngeal symptoms via vagal mechanisms in patients with laryngopharyngeal reflux disease, concludes "tVNS emerges as a potentially accessible and cost-effective adjunctive therapy for individuals with LPRD."

Page updated 20 April 2025