H-Pylori

Helicobacter Pylori

H-Pylori is a bacterium commonly found in the stomach.

This 2014 study, Epidemiology of Helicobacter pylori infection, found "In north European and North American populations, about one-third of adults are still infected, whereas in south and east Europe, South America, and Asia, the prevalence of H. pylori is often higher than 50%." "Although the way the infection is transmitted is still unclear, interpersonal transmission appears to be the main route."

We do not know exactly how the organism spreads but its incidence is higher in areas of low socioeconomic conditions in childhood. Moreover, probably due to healthier lifestyles and access to cleaner living conditions, the prevalence is lower amongst younger ages.

In order to survive in the harsh environment, the bacteria burrow into the gastric mucosa lining the stomach.

In this factsheet from Guts UK, Helicobacter pylori, they state,"About 40% of people in the UK have Helicobacter pylori in their stomach so it is very common and in the approximately 8 to 9 out of 10 people who have it, does not cause any problems."

However, for those where it is a problem, in an attempt to eradicate the invader, the stomach may produce extra acid which can cause gastritis or, if it refluxes, exacerbate oesophagitis.

This 2023 paper in Frontiers of Oncology, Unwelcome guests – the role of gland-associated Helicobacter pylori infection in gastric carcinogenesis, suggests, "a subpopulation of H. pylori can invade deep into the gastric glands and directly interact with progenitor and stem cells... [and] point towards a critical role of gland-associated H. pylori in the development of gastric cancer."

It is usual to test for H-Pylori by blood test, breath test, stool test or during endoscopy.

Eradication treatment of H-Pylori is by a combination of 2 different antibiotics and an acid suppressant.

Page updated 8 May 2023