1814

 The Cherokee, Choctaw, and Creek (Muscogee) join as US allies in a military campaign against Red Sticks, a confederate faction that had allied with Tecumseh, a Shawnee chief who was fighting with the British against the United States, killed about 250 militia men and civilians at Fort Mims in retaliation for an ambush by American militia at Burnt Corn Creek.[86]

Andrew Jackson headed south from Fayetteville, Tennessee, in October with 2,500 militia, establishing Fort Strother as his supply base.[88] He sent his cavalry under General Coffee ahead of the main force, destroying Red Stick villages and capturing supplies.[89][90] Coffee defeated a band of Red Sticks at the Battle of Tallushatchee on November 3, and Jackson defeated another band later that month at the Battle of Talladega.[91]

By January 1814, the expiration of enlistments and desertion had reduced Jackson's force by about 1,000 volunteers, but he continued the offensive.[93] The Red Sticks counterattacked at the Battles of Emuckfaw and Enotachopo Creek. Jackson repelled them but was forced to withdraw to Fort Strother.[94] Jackson's army was reinforced by further recruitment and the addition of a regular army unit, the 39th U.S. Infantry Regiment. The combined force of 3,000 men—including  Cherokee, Choctaw, and Muscogee allies—attacked a Red Stick fort at Horseshoe Bend on the Tallapoosa River, which was manned by about 1,000 men.[95] The Red Sticks were overwhelmed ...and massacred. 

Nearly 300 women and children were taken prisoner and distributed to Jackson's Native American allies.[96] The victory broke the power of the Red Sticks.[97] Jackson continued his scorched-earth campaign of burning villages, destroying supplies,[97] and starving Red Stick women and children.[98] The campaign ended when William Weatherford, the Red Stick leader, surrendered,[99] although some Red Sticks fled to East Florida.

...

Following the Battle of Pensacola, Battle of New Orleans & First Seminole War Jackson remained in command of troops in the southern half of the United States and was permitted to make his headquarters at the Hermitage.[129] Jackson continued to displace the Native Americans in areas under his command:

• 1816 - 1820 Jackson  signed five treaties in which the Creek, Choctaw, Cherokee and Chickasaw ceded tens of millions of acres of land to the United States, despite resistance from Secretary of the Treasury William Crawford. These included the Treaty of Tuscaloosa and the Treaty of Doak's Stand.[130][131] 

• Jackson's occupation of Pensacola would lead Spain to sell Florida, which Spain did in the Adams–Onís Treaty of 1819.[140] In February 1819, a congressional investigation exonerated Jackson,[141] and 

• 1823 - Jackson's victory was instrumental in convincing the Seminoles to sign the Treaty of Moultrie Creek in, which surrendered much of their land in Florida.[142]