Publications

1) Teng O, Ang CKE and Guan XL# (2017) Macrophage–Bacteria Interactions—A Lipid-Centric Relationship. Front. Immunol. 8:1836. doi: 10.3389/fimmu.2017.01836. # Correspondence.

2) Guan XL#, Maeser P. Comparative sphingolipidomics of trypanosomatids reveal lifecycle- and taxonomy-specific lipid chemistries. Scientific Reports. 7(13617). DOI:10.1038/s41598-017-13931-x. # Correspondence.

3) Crick PJ and Guan XL# (2016). Lipid metabolism in mycobacteria--Insights using mass spectrometry-based lipidomics. BBA-Molecular and Cell Biology of Lipids. 1861(1):60-67. Invited review. # Correspondence.

4) Vögtle FN, Keller M, Prinz C, Guan XL, van der Laan M, Wenk MR, Schubert R, Wiedemann N, Holzer M, Meisinger C (2015). The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1. Journal of Cell Biology. 210(6):951-60. (IF: 9.834, citation:12)

5) Luisoni S, Soumalainen M, Boucke K, Tanner LB, Wenk MR, Guan XL, Grzybeck M, Coskun U, Greber UF (2015). Co-option of Membrane Wounding and Ceramide Lipid Signaling Enables Virus Penetration into Cells. Cell Host and Microbe.18:75-85. (Independent work from Wenk MR) (IF:12.609,citation:29)

6) Fügi M, Kaiser M, Tanner M, Schneiter R, Mäser P, Guan XL# (2015). Match-making for Posaconazole through systems-thinking. Trends in Parasitology. 32(2):46-51. # Correspondence.(IF:6.217,citation:5)

7) Portevin D, Sukumar S, Coscolla M, Shui G, Li B, Guan XL, Bendt AK, Young D. Gagneux S, Wenk MR (2014). Lipidomics and genomics of M. tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis. Microbiology Open. 3(6):823-35. (IF: 2.213, citation:13)

8) Tanner LB, Chng C, Guan XL, Lei Z, Rozen SG. Wenk MR (2014). Lipidomics identifies a requirement of host cell choline lipid metabolism for influenza virus replication. Journal of Lipid Research.55(7):1357-1365. (IF:4.73, citation:19)

9) Fügi M, Gunasekera K, Ochsenreiter T, Guan XL, Wenk MR, Mäser P (2014). Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack. Journal of Lipid Research. 55(5):929-938. (IF:4.73, citation:10)

10) Hadidi N, Soh KC, Pedarsani P, Seijo M, Guan XL, Wenk MR, Hatzimanikatis V (2014). NICELips: A computational framework for reconstructing lipid metabolism. Metabolic Engineering. 23:1-8. (IF:8.258, citation:9)

11) Guan XL#, Cestra G, Shui G, Kuhrs A, Schittenhelm RB, Hafen E, van der Goot FG, Robinett CC, Gatti M, Gonzalez-Gaitan M, Wenk MR (2013). Biochemical membrane lipidomics during Drosophila development. Developmental Cell. 24(1): 98-111. # Co-correspondence. (IF:9.708, citation:51)

12) Guan XL#, Wenk MR (2012). Targeted and non-targeted analysis of membrane lipids using mass spectrometry. Methods Cell Biol. 108: 149-172. # Co-correspondence. (IF:1.44, citation:4)

13) Zhang Q, Hunk C, Yau Y, Seow V, Lee S, Tanner LB, Guan XL, Wenk MR, Chew P, Kukkaro P, Biukovic, Shi P, Shochat SG, Grüber, G, Lok S (2012). The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation. Journal of Biological Chemistry. 287(48):40525-40534. (IF:4.6, citation:20)

14) Souza CM, Pichler H, Leitner E, Guan XL, Wenk MR, Jeannerat D, Tornare I and Riezman H (2011). Cholesterol can replace ergosterol for tryptophan uptake, but not weak organic acid resistance in yeast. Metabolic Engineering. 13(5). 555-569. (IF:8.258, citation:22)

15) Lissina E, Lowenson J, Young B, Guan XL, Baryshnikova A, Urbanus M, Hoon S, Riezman I, Boone C, Cowen L, Riezman H, Wenk MR, Clarke S, Giaever G, Nislow C (2011). A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. PLoS Genet. 7(10):e1002332. (IF:8.167, citation:14)

16) Guan XL, Riezman I, Wenk MR, Riezman H (2010). Yeast Lipid Analysis and Quantitation by Mass Spectrometry. Methods in Enzymology. 470: 369-391. (IF:2.088, citation:50)

17) Young BP, Shin JJH, Orij R, Chao JT, Li SC, Guan XL, Khong A, Jan E, Wenk MR, Prinz WA, Smits GJ, Loewen CJR (2010). Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. Science. 329(5995):1085-8. (IF:33.611, citation:160)

18) Shui G, Guan XL, Gopalakrishnan P, Xue Y, Goh JSY, Yang H, Wenk MR (2010). Characterization of substrate preference for Slc1 and Cst26 using sensitive fatty acyl-based multiple reaction monitoring approach. Plos One. 5(8). pii: e11956. (IF:3.234, citation:29)

19) Shui G, Guan XL, Low CP, Chua GH, Goh JSY, Yang H, Wenk MR (2010). Towards one step analysis of major cellular lipidome using liquid chromatography coupled to mass spectrometry. Molecular Biosystems. 6(6):1008-17. (IF:3.183, citation:69)

20) Gebert N, Joshi AS, Kutik S, Becker T, McKenzie M, Guan XL, Wenk MR, Rehling P, Meisinger C, Ryan MT, Wiedemann N, Greenberg ML, Pfanner N (2009). Mitochondrial cardiolipin involved in outer membrane protein biogenesis: implications for Barth syndrome. Current Biology. 19(24): 2133-9. (IF:9.571, citation:141)

21) Kohler K, Brunner E, Guan XL, Boucke K, Greber UF, Mohanty S, Barth J, Wenk MR and Hafen E (2009). A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation induced autophagy in Drosophila. Autophagy. 5(7):980-990. (IF:12.042, citation:39)

22) Guan XL, Souza CM, Pichler H, Dewhurst G, Schaad O, Kajiwara K, Wakabayashi H, Ivanova T, Castillon GA, Piccolis M, Abe F, Loewith R, Funato K, Wenk MR and Riezman H (2009). Functional interactions between sphingolipids and sterols regulating cell physiology. Mol. Biol. Cell. 20(7):2083-95. * Awarded MBC paper of the year, 2009. ** Featured as ‘MBoC 20th Anniversary Favourite’, 2012. (IF:4.803, citation:137)

23) Guan XL and Wenk MR (2008). Biochemistry of inositol lipids. Frontiers in Bioscience. 13: 3239-3251. (IF:3.9, citation:18)

24) Kutik S, Rissler M, Guan XL, Guiard B, Shui G, Gebert N, Heacock P, Rehling P, Dowhan W, Wenk MR, Pfanner N and Wiedemann N (2008). The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. Journal of Cell Biology. 183(7): 1213-21. (IF:9.786, citation:85)

25) Mousley CJ, Tyeryar K, He KE, Schaaf G, Brost R, Boone C, Guan XL, Wenk MR and Bankaitis VA (2008). Coordinate defects in Sec14 and Tlg2-dependent trans-Golgi and endosome dynamics derange ceramide homeostasis and compromise the unfolded protein response. Mol. Biol. Cell. 19(11): 4785-803. (IF:4.803, citation:41)

26) He X, Guan XL*, Ong WY, Farooqui AA and Wenk MR (2007). Expression, activity, and role of serine palmitoyltransferase in the rat hippocampus after kainate injury. J Neurosci Res. 85(2): 423-32. *Co-first author. (IF:2.974, citation:18)

27) Guan XL, He X, Ong WY, Yeo WK, Shui G and Wenk MR (2006). Non-targeted profiling of lipids during kainate induced neuronal injury. FASEB J. 20(8): 1152-61. (IF:5.043, citation:78)

28) Guan XL and Wenk MR (2006). High resolution and targeted profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae. Yeast. 23(6): 465-77. (IF:1.955, citation:104)

29) Chee JL, Guan XL, Lee JY, Dong B, Leong SM, Ong EH, Liou AK and Lim TM (2005). Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons. Cell. Mol. Life Sci. 62(2): 227-38. (IF:5.808, citation:30)