East Midlands Commercial Collaborative (EMCC) Dementia Research Offering
The East Midlands is home to five community and mental health NHS trusts that are members of the East Midlands Commercial Collaborative (EMCC).
The EMCC trusts provide a unique collaborative offering across the region to support the delivery of commercial dementia research. We have a large patient population across six counties and together we are dedicated to providing opportunities for this population to influence and take part in dementia research.
Contact the National Institute for Health and Care Research (NIHR) Clinical Research Network (CRN) East Midlands to discuss how the EMCC can deliver your dementia clinical trials: supportmystudyeastmidlands@nihr.ac.uk.
Research Assets
Dedicated clinical research spaces
Access to pathology, imaging, lumbar puncture services, plus others
Established pathways with Primary Care, Care Homes and other third sector services
Active projects to engage under-served communities in research
Collaborations with private providers and acute trusts to deliver a wide range of study designs
Patient Population
The East Midlands has a population of nearly five million people and has one of the highest prevalences of dementia in England, with 8.40 people per 1,000 living with dementia
Our Experience
We are decentralised clinical trial ready, with experience in:
Digital recruitment
Virtual/telephone visits and remote consent
Remote monitoring
Use of various digital devices and apps for monitoring patients at home
Our Organisations
Derbyshire Healthcare NHS Foundation Trust
Leicestershire Partnership NHS Trust
Lincolnshire Partnership NHS Foundation Trust
Northamptonshire Healthcare NHS Foundation Trust
Nottinghamshire Healthcare NHS Foundation Trust
Key Sites
The East Midlands is home to a number of geographically spread sites with experience and expertise in delivering dementia studies.
Covering every county across the region, these sites offer the potential for engagement with a wide range of research participants including people from under-served communities.
Collectively, this strong regional infrastructure enables the sharing of information and best practice to empower staff to deliver high quality research studies.
Join Dementia Research
Join Dementia Research offers a source of potential participants for your dementia trial.
Join Dementia Research is a service that connects people to dementia studies.
The service is actively promoted in the East Midlands. There are over 4000 volunteers across the region who have already registered their interest in taking part in dementia research.
Find more information about JDR here.
Since 2018
1,591
patients recruited into 78 dementia studies
24,587
patients recruited into 556 studies overall
Streamlined study set-up
in line with sponsor expectations
Meet the Team
Professor Tom Denning
Specialty Lead for Dementia and Neurodegeneration
East Midlands
"The East Midlands is home to a number of organisations with a strong track record in delivering dementia research studies. Alongside a diverse regional populational spread, our partner organisations pride themselves on their flexibility and adaptability, ensuring that studies can quickly be set up for efficient recruitment and the meeting of targets. "
Dr Paul Koranteng
Consultant Old Age Psychiatrist and Clinical Director Older People's Mental Health
Northamptonshire Healthcare NHS Trust
"We are proud of the research workforce across our region, many of whom are experienced in delivering high quality commercial research, including dementia studies. We are continually developing the skills and support that we provide to researchers in order to ensure that our partners, and people taking part in studies in the East Midlands, have the best possible experience."
Our Researchers
Dr Kehinde Junaid
Consultant Old Age Psychiatrist (Nottinghamshire Healthcare NHS Foundation Trust)
Professor Elizabeta Mukaetova-Ladinska
Professor in Old Age Psychiatry (University of Leicester and MHSOP, Leicester Partnership NHS Foundation Trust)
Dr Mohan Rathnaiah
Consultant in Liason & Neuropsychiatry (Derbyshire Healthcare NHS Foundation Trust)
Dr Collins Esiwe
Clinical Director for Older Adult and Frailty Division (Lincolnshire Partnership NHS Foundation Trust)
East Midlands Collaboration
Mark Howells, Head of Research and Evidence at Nottinghamshire Healthcare NHS Foundation Tust:
"With a large patient population and a wealth of experience in supporting commercial research, the community and mental healthcare providers in the East Midlands are poised to deliver your study. We have access to high-quality research sites, a strong history of collaboration with a range of different organisations, and a commitment to continually adapting research processes to improve research delivery for partners and participants alike. We would welcome the opportunity to speak to you and explore how we can work together across our region. "
We are proud to deliver a portfolio of high quality studies that range from observational and CTIMPs to medical and digital device studies:
MADE (minocycline in early Alzheimer's disease): Recruitment of 164 patients into this Phase 2 CTIMP study
PrAISED (promoting activity, independence and stability in early dementia): The EMCC recruited >70% of the UK recruits for this study
SERVIER (An international, multicentre, randomised, doubleblind, Placebocontrolled phase IIb study): The first UK site to open and recruit into this commercial Alzheimer's study comparing the safety and efficacy of an IMP was a member of the EMCC
FREE-COG (A novel, free to use, measure of combined cognitive and functional abilities for clinical use): This study evaluated dementia screening equipment and produced evidence that led to it's adoption
DEME (A drug utilisation study in patients treated with rivastigmine transdermal patch): The first site to open and recruit into this commercial non-interventional study was within the EMCC and recruited 140% of their recruitment target
What Our Participants Say
"I have been kept fully informed prior to the research starting and have been treated professionally at each visit by the members of the research team I have seen. "
"Informative and responsive to any queries. Friendly and professional staff when attending appointments. Great communication and effective planning."
Exciting Initiatives in the East Midlands
We have a regional rater group and our rater scale experienced staff support each other across the region and across Trust boundaries.
This collaborative ethos helps to facilitate the successful delivery of research regionally.
The Lincolnshire Joint Strategy for Dementia emphasises the need for a whole system approach across the NHS, adult social care, public health, the independent and voluntary sector, and beyond, in order to identify the needs of people with dementia, and those at risk of dementia.
The Centre for Dementia is an academic centre of excellence for dementia research that has been set up within the Institute of Mental Health (a collaboration between Nottinghamshire Healthcare NHS Foundation Trust and the University of Nottingham).