GHRP-2 is a growth hormone-releasing peptide that has been shown to mimic the effects of ghrelin in the way that it increases appetite and stimulates the release of growth hormone. A study conducted by Peroni et. Al, examined the effect that two different dosages of GHRP-2 had on growth hormone secretion and overall body weight of mice.
In the initial experiment conducted by the researchers, wild-type C57BL mice were injected with either 1 microgram of GHRP-2 or 10 micrograms of GHRP-2. Following the injection, the mice were euthanized and their blood was collected for up to 1 hour after injection at various different points in time to measure the amount of growth hormone in the body. Results of the first study showed that the C57BL mice injected with 10 micrograms elicited a far stronger secretion in GH than the mice injected with 1 microgram. Furthermore, the results of the study showed that GH secretion reached a peak of 163 ng/ml about 5-10 after the initial injection. It was shown that 20 minutes after the injection levels of GH returned to their baseline levels.