Fragment 176-191 is a peptide that is a molecular fragment of Human Growth Hormone (HGH) consisting of 16 amino acids attached to the C-terminus of positions 176 and 191. It is most commonly known for its lipolytic activity and ability to suppress the development of new body fat.
Fragment 176-191 is commonly referred to as a lipolytic fragment due to the dramatic weight loss effects it has exhibited in animal-based studies. The fat-burning and weight loss properties are seemingly driven by the increased production of beta-3-adrenergic receptors (ADRB3) that are commonly linked to fat burning in adipose tissue and thermogenesis in skeletal muscles.