Think of Fresh Foam as New Balance's competitor to Adidas Boost and Nike React. Fresh Foam cushioning provides the wearer with ultra-soft, smooth support in a lightweight package. Fresh Foam cushions the high impact foot strikes that occur on a variety of surfaces. It does, however, lack in stability and support. Fresh foam can be found in lifestyle models, but it is mostly used in performance running shoes and some work shoes. Get Fresh Foam if you mostly care about softness and cushioning. If you love Fresh Foam, but still want more stability and support, go with Fresh Foam X.
The comfort of the shoe is not only based on the technology used, but the overall shape and size of the midsole and outsole too. Some models utilize more Fresh Foam than others. Comfort will vary from model to model.